Epoxidation, 3,3-dimethylbutanal, 2-chloro-3,4-dihydronaphthalen-1(2H)-one, (2S,3’R)-3′-neopentyl-3,4-dihydro-1H-spiro[naphthalene-2,2′-oxiran]-1-one, 9-hydroxy-1-[[4-(trifluoromethyl)phenyl]methyl]-(9S)-Cinchonanium bromide, Cinchonine DerivativeEpoxidation alpha-Alkylation, 1-benzhydryl-3-(6-(benzyloxy)benzo[d][1,3]dioxol-5-yl)indolin-2-one, ((chloromethoxy)methyl)benzene, (R)-1-benzhydryl-3-(benzyloxy)-3-(6-(benzyloxy)benzo[d][1,3]dioxol-5-yl)indolin-2-one, (9S)-1-(9-anthracenylmethyl)-9- hydroxy-cinchonanium bromide, Cinchonine DerivativeAlkylation, alpha-Alkylation alpha-Alkylation, 6,7-dichloro-5-methoxy-2-phenyl-2,3-dihydro-1H-inden-1-one, chloromethane, (S)-6,7-dichloro-5-methoxy-2-methyl-2-phenyl-2,3-dihydro-1H-inden-1-one, 9-hydroxy-1-[[4-(trifluoromethyl)phenyl]methyl]-(9S)-Cinchonanium bromide, Cinchonine DerivativeAlkylation, alpha-Alkylation Epoxidation, aldehydes, 1-chloroalkan-2-one, 3-substituted 1-((3R)-3-methyloxiran-2-yl)alkan-1-one, 9-hydroxy-1-[[4-(trifluoromethyl)phenyl]methyl]-(9S)-Cinchonanium bromide, Cinchonine DerivativeEpoxidation Allylic Alkylation, (E)-N,1-diphenylmethanimine, allyltributylstannane, (R)-N-(1-phenylbut-3-en-1-yl)aniline, 1-(chloromethyl)-4-fluoro-1,4-Diazoniabicyclo[2.2.2]octane tetrafluoroborate(1-), 1-fluoro-9-hydroxy-(9S)-Cinchonanium tetrafluoroborate(1-), Cinchonine DerivativeAlkylation, Allylic Alkylation Oxysulfonylation, 3-substituted (1Z,3E)-N-hydroxypent-3-enimidoyl, alkyl sulfonyl chloride, substituted (1S)-1-((R)-3,5-disubstituted-4,5-dihydroisoxazol-5-yl)ethane-1-sulfinate, N-(9R)-Cinchonan-9-yl-2,3-dihydro- 2,2,4,5,7-pentamethyl-6-benzofuran sulfonamide, Cinchonine DerivativeCyclization, Further reactions, Isoxazoline cyclization, Oxysulfonylation, Sulfonylation Mannich reaction, substituted P,P-diphenyl-N-(propan-2-ylidene)phosphinic amide, methyl 2-isocyanoacetate, 5-substituted methyl (4R,5R)-1-(diphenylphosphoryl)-5-methyl-4,5-dihydro-1H-imidazole-4-carboxylate, N-(9R)-cinchonan-9-yl-4-(trifluoromethyl)-2-Pyridinecarboxamide, Cinchonine DerivativeMannich, Mannich Hydrophosphorylation, ((2R,3S)-2,3-disubstituted-1-yl)(pyridin-3-yl)methanone, diphenyl phosphonate, diphenyl ((1S,2R)-1,2-disubstituted-2-(nicotinamido)ethyl)phosphonate, N-(9R)-Cinchonan-9-yl-2-pyridinecarboxamide, Cinchonine DerivativeHydrophosphonylation Michael addition, pentane-2,4-dione, (E)-(2-nitrovinyl)benzene, (R)-3-(2-nitro-1-phenylethyl)pentane-2,4-dione, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]- 4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione, Cinchonine DerivativeMichael, Michael Addition Monofluoromethylation, phenyl(2-(p-tolyl)indolin-3-yl)methanesulfonyl tolyl, (fluoromethylenedisulfonyl)dibenzene, 3-((S)-2-fluoro-1-phenyl-2,2-bis(phenylsulfonyl)ethyl)-2-(p-tolyl)indoline, 1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]- 9-hydroxy-(9S)-Cinchonanium bromide (1:1), Cinchonine DerivativeFurther reactions, Monofluoro-methylation« Older EntriesNext Entries »
Epoxidation, 3,3-dimethylbutanal, 2-chloro-3,4-dihydronaphthalen-1(2H)-one, (2S,3’R)-3′-neopentyl-3,4-dihydro-1H-spiro[naphthalene-2,2′-oxiran]-1-one, 9-hydroxy-1-[[4-(trifluoromethyl)phenyl]methyl]-(9S)-Cinchonanium bromide, Cinchonine DerivativeEpoxidation
alpha-Alkylation, 1-benzhydryl-3-(6-(benzyloxy)benzo[d][1,3]dioxol-5-yl)indolin-2-one, ((chloromethoxy)methyl)benzene, (R)-1-benzhydryl-3-(benzyloxy)-3-(6-(benzyloxy)benzo[d][1,3]dioxol-5-yl)indolin-2-one, (9S)-1-(9-anthracenylmethyl)-9- hydroxy-cinchonanium bromide, Cinchonine DerivativeAlkylation, alpha-Alkylation
alpha-Alkylation, 6,7-dichloro-5-methoxy-2-phenyl-2,3-dihydro-1H-inden-1-one, chloromethane, (S)-6,7-dichloro-5-methoxy-2-methyl-2-phenyl-2,3-dihydro-1H-inden-1-one, 9-hydroxy-1-[[4-(trifluoromethyl)phenyl]methyl]-(9S)-Cinchonanium bromide, Cinchonine DerivativeAlkylation, alpha-Alkylation
Epoxidation, aldehydes, 1-chloroalkan-2-one, 3-substituted 1-((3R)-3-methyloxiran-2-yl)alkan-1-one, 9-hydroxy-1-[[4-(trifluoromethyl)phenyl]methyl]-(9S)-Cinchonanium bromide, Cinchonine DerivativeEpoxidation
Allylic Alkylation, (E)-N,1-diphenylmethanimine, allyltributylstannane, (R)-N-(1-phenylbut-3-en-1-yl)aniline, 1-(chloromethyl)-4-fluoro-1,4-Diazoniabicyclo[2.2.2]octane tetrafluoroborate(1-), 1-fluoro-9-hydroxy-(9S)-Cinchonanium tetrafluoroborate(1-), Cinchonine DerivativeAlkylation, Allylic Alkylation
Oxysulfonylation, 3-substituted (1Z,3E)-N-hydroxypent-3-enimidoyl, alkyl sulfonyl chloride, substituted (1S)-1-((R)-3,5-disubstituted-4,5-dihydroisoxazol-5-yl)ethane-1-sulfinate, N-(9R)-Cinchonan-9-yl-2,3-dihydro- 2,2,4,5,7-pentamethyl-6-benzofuran sulfonamide, Cinchonine DerivativeCyclization, Further reactions, Isoxazoline cyclization, Oxysulfonylation, Sulfonylation
Mannich reaction, substituted P,P-diphenyl-N-(propan-2-ylidene)phosphinic amide, methyl 2-isocyanoacetate, 5-substituted methyl (4R,5R)-1-(diphenylphosphoryl)-5-methyl-4,5-dihydro-1H-imidazole-4-carboxylate, N-(9R)-cinchonan-9-yl-4-(trifluoromethyl)-2-Pyridinecarboxamide, Cinchonine DerivativeMannich, Mannich
Hydrophosphorylation, ((2R,3S)-2,3-disubstituted-1-yl)(pyridin-3-yl)methanone, diphenyl phosphonate, diphenyl ((1S,2R)-1,2-disubstituted-2-(nicotinamido)ethyl)phosphonate, N-(9R)-Cinchonan-9-yl-2-pyridinecarboxamide, Cinchonine DerivativeHydrophosphonylation
Michael addition, pentane-2,4-dione, (E)-(2-nitrovinyl)benzene, (R)-3-(2-nitro-1-phenylethyl)pentane-2,4-dione, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]- 4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione, Cinchonine DerivativeMichael, Michael Addition
Monofluoromethylation, phenyl(2-(p-tolyl)indolin-3-yl)methanesulfonyl tolyl, (fluoromethylenedisulfonyl)dibenzene, 3-((S)-2-fluoro-1-phenyl-2,2-bis(phenylsulfonyl)ethyl)-2-(p-tolyl)indoline, 1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]- 9-hydroxy-(9S)-Cinchonanium bromide (1:1), Cinchonine DerivativeFurther reactions, Monofluoro-methylation
