Desymmetrization, (3aR,6aS)-tetrahydro-1H-cyclopenta[c]furan-1,3(3aH)-dione, methanol, (1R,2S)-2-(methoxycarbonyl)cyclopentane-1-carboxylic acid, Quinidine BaseDesymmetrization Desymmetrization, cyclic meso-anhydrides, methanol, 2-substituted (1R,3S)-3-(methoxycarbonyl)cyclopropane-1-carboxylic acid, Quinidine BaseDesymmetrization oxa-Michael, 2,5-cyclohexadienone-tethered aryl aldehydes, hydroperoxyalkanes, cyclohexenone-fused isochromans, Quinidine BaseCyclization, Desymmetrization, Further Cyclizations, Intramolecular cyclization, Michael Addition, Oxa-Michael Addition Isomerization, substituted (E)-3,5-dimethylhex-3-en-2-one, substituted 3,5-dimethylhex-4-en-2-one, Quinidine BaseIsomerization Trifluoromethylthiolation, beta-keto esters, N-trifluoromethylthiophthalimide, tert-butyl (S)-4-methyl-2-oxo-1-((trifluoromethyl)thio)cyclopent-3-ene-1-carboxylate, Quinidine BaseTrifluoro-methylthiolation Cyanation, activated olefins, ethyl cyanoformate, R-substituted diethyl 2-(1-cyanomethyl)malonate, Tetraisopropyl Titanate, 3,3′-disubstituted-[1,1′-biphenyl]-2,2′-diol, Quinidine BaseCyanation, Michael, Michael Addition Vinylogous Michael Addition, alpha,beta-unsaturated γ-butyrolactam, nitroolefins, 1R-substituted tert-butyl (R)-2-(2-nitroethyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate, Quinidine BaseMichael Addition, Vinylogous Michael Addition Protonation, alpha‐oxygenated ester enolates, disubstituted phosphonic acid, substituted (R)-2-(phosphonooxy)propanoate, Quinidine BaseFurther reactions, Protonation Sulfenylation, 3-substituted oxindoles, substituted 2-(phenylthio)isoindoline-1,3-dione, substituted tert-butyl (R)-2-oxo-3-phenyl-3-(phenylthio)indoline-1-carboxylate, Quinidine BaseSulfenylation Michael Addition, substituted (E)-3-(prop-1-en-1-yl)benzo[d]isothiazole 1,1-dioxide, malononitrile, (9S)-substituted 7-amino–9H-benzo[4,5]isothiazolo[2,3-a]pyridine-8-carbonitrile 5,5-dioxide, Quinidine BaseAza-Michael, Cyclization, Cyclization, Further Cyclizations, Michael Addition« Older EntriesNext Entries »
Desymmetrization, (3aR,6aS)-tetrahydro-1H-cyclopenta[c]furan-1,3(3aH)-dione, methanol, (1R,2S)-2-(methoxycarbonyl)cyclopentane-1-carboxylic acid, Quinidine BaseDesymmetrization
Desymmetrization, cyclic meso-anhydrides, methanol, 2-substituted (1R,3S)-3-(methoxycarbonyl)cyclopropane-1-carboxylic acid, Quinidine BaseDesymmetrization
oxa-Michael, 2,5-cyclohexadienone-tethered aryl aldehydes, hydroperoxyalkanes, cyclohexenone-fused isochromans, Quinidine BaseCyclization, Desymmetrization, Further Cyclizations, Intramolecular cyclization, Michael Addition, Oxa-Michael Addition
Isomerization, substituted (E)-3,5-dimethylhex-3-en-2-one, substituted 3,5-dimethylhex-4-en-2-one, Quinidine BaseIsomerization
Trifluoromethylthiolation, beta-keto esters, N-trifluoromethylthiophthalimide, tert-butyl (S)-4-methyl-2-oxo-1-((trifluoromethyl)thio)cyclopent-3-ene-1-carboxylate, Quinidine BaseTrifluoro-methylthiolation
Cyanation, activated olefins, ethyl cyanoformate, R-substituted diethyl 2-(1-cyanomethyl)malonate, Tetraisopropyl Titanate, 3,3′-disubstituted-[1,1′-biphenyl]-2,2′-diol, Quinidine BaseCyanation, Michael, Michael Addition
Vinylogous Michael Addition, alpha,beta-unsaturated γ-butyrolactam, nitroolefins, 1R-substituted tert-butyl (R)-2-(2-nitroethyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate, Quinidine BaseMichael Addition, Vinylogous Michael Addition
Protonation, alpha‐oxygenated ester enolates, disubstituted phosphonic acid, substituted (R)-2-(phosphonooxy)propanoate, Quinidine BaseFurther reactions, Protonation
Sulfenylation, 3-substituted oxindoles, substituted 2-(phenylthio)isoindoline-1,3-dione, substituted tert-butyl (R)-2-oxo-3-phenyl-3-(phenylthio)indoline-1-carboxylate, Quinidine BaseSulfenylation
Michael Addition, substituted (E)-3-(prop-1-en-1-yl)benzo[d]isothiazole 1,1-dioxide, malononitrile, (9S)-substituted 7-amino–9H-benzo[4,5]isothiazolo[2,3-a]pyridine-8-carbonitrile 5,5-dioxide, Quinidine BaseAza-Michael, Cyclization, Cyclization, Further Cyclizations, Michael Addition
