Amination, fluorinated keto esters, di‐tert‐butyl azodicarboxylate, diethyl (R)-1-(2-fluoro-1-methoxy-1,3-dioxo-3-phenylpropan-2-yl)hydrazine-1,2-dicarboxylate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-guanidine, Quinidine Derivativealpha-Amination, Amination Amination, 1,3-dibenzylindolin-2-one, di‐tert‐butyl azodicarboxylate, diethyl (S)-1-(1,3-dibenzyl-2-oxoindolin-3-yl)hydrazine-1,2-dicarboxylate, (9S)-(9′′S)-9,9′′-[[5-[4-[1-(phenylmethyl)-1H-1,2,3-triazol-4-yl]butyl]- 3,6-pyridazinediyl]bis(oxy)]bis[6′-methoxy-cinchonan, Quinidine Derivativealpha-Amination, Amination Iodoetherification, substituted β,γ-unsaturated oximes, N-iodosuccinimide, substituted 2-isoxazolines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydrocinchonan-9-yl]thiourea, Dihydrocinchonidine DerivativeCyclization, Iodination, Iodoetherification, Isoxazoline cyclization Friedel Crafts Alkylation, methyleneoxindoles, hydroxyindoles, substituted tert-butyl (2-((3R,4S)-2-oxo-2,3,4,7-tetrahydropyrano[2,3-e]indol-3-yl)phenyl)carbamate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeFriedel-Crafts, Friedel-Crafts alkylation/lactonization, Lactonization Cascade reaction, substituted 4-oxo-4H-chromene-3-carbaldehyde, substituted tert-butyl (E)-2-(1-acetyl-2-oxoindolin-3-ylidene)acetate, substituted tert-butyl (1’S,2’S,3S,3’R,4a’R,9a’S)-1-acetyl-1′-hydroxy-2′-nitro-9′-oxo-2′,3′,4a’,9a’-tetrahydro-1’H,9’H-spiro[indoline-3,4′-xanthene]-3′-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCascade reaction Michael Addition, (E)-1-(4-chlorophenyl)-3-phenylprop-2-en-1-one, ((nitromethyl)sulfonyl)benzene, (3R)-1-(4-chlorophenyl)-4-nitro-3-phenyl-4-(phenylsulfonyl)butan-1-one, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeMichael, Michael Addition Cascade reaction, 3-Aminooxindoles, Isatin-Derived β,γ-Unsaturated α-Keto Esters, 3,3′-Pyrrolidinyl-bispirooxindoles, 3-[[(8α,9S)-10,11-Dihydrocinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Dihydrocinchonidine DerivativeCascade reaction Cascade reaction, enynones, pyrazolones, pyranopyrazolones, (8α,9R)-6′-[[Tris(1-methylethyl)silyl]oxy]cinchonan-9-ol, Cupreine DerivativeCascade reaction Intramolecular aza-Wacker oxidation cyclization, aromatic nitrogen‐containing dienes, dihydroindole nitrogen‐ containing polycyclic compounds, (9S)-2′-[(4S)-4-(1,1-Dimethylethyl)-4,5-dihydro-2-oxazolyl]-9-methoxycinchonan, Cinchonine DerivativeCyclization, Further Cyclizations, Further reactions, Intramolecular aza-Wacker oxidation cyclization, Intramolecular cyclization Intramolecular aza-Wacker oxidation cyclization, N-(2-cinnamylphenyl)acrylamide, (1S,9aR)-2-methylene-1-phenyl-1,2,9,9a-tetrahydro-3H-pyrrolo[1,2-a]indol-3-one, (8α,9R)-2′-[(4S)-4-(1,1-Dimethylethyl)-4,5-dihydro-2-oxazolyl]-9-methoxycinchonan, Cinchonidine DerivativeCyclization, Further Cyclizations, Intramolecular aza-Wacker oxidation cyclization, Intramolecular cyclization« Older EntriesNext Entries »
Amination, fluorinated keto esters, di‐tert‐butyl azodicarboxylate, diethyl (R)-1-(2-fluoro-1-methoxy-1,3-dioxo-3-phenylpropan-2-yl)hydrazine-1,2-dicarboxylate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-guanidine, Quinidine Derivativealpha-Amination, Amination
Amination, 1,3-dibenzylindolin-2-one, di‐tert‐butyl azodicarboxylate, diethyl (S)-1-(1,3-dibenzyl-2-oxoindolin-3-yl)hydrazine-1,2-dicarboxylate, (9S)-(9′′S)-9,9′′-[[5-[4-[1-(phenylmethyl)-1H-1,2,3-triazol-4-yl]butyl]- 3,6-pyridazinediyl]bis(oxy)]bis[6′-methoxy-cinchonan, Quinidine Derivativealpha-Amination, Amination
Iodoetherification, substituted β,γ-unsaturated oximes, N-iodosuccinimide, substituted 2-isoxazolines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydrocinchonan-9-yl]thiourea, Dihydrocinchonidine DerivativeCyclization, Iodination, Iodoetherification, Isoxazoline cyclization
Friedel Crafts Alkylation, methyleneoxindoles, hydroxyindoles, substituted tert-butyl (2-((3R,4S)-2-oxo-2,3,4,7-tetrahydropyrano[2,3-e]indol-3-yl)phenyl)carbamate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeFriedel-Crafts, Friedel-Crafts alkylation/lactonization, Lactonization
Cascade reaction, substituted 4-oxo-4H-chromene-3-carbaldehyde, substituted tert-butyl (E)-2-(1-acetyl-2-oxoindolin-3-ylidene)acetate, substituted tert-butyl (1’S,2’S,3S,3’R,4a’R,9a’S)-1-acetyl-1′-hydroxy-2′-nitro-9′-oxo-2′,3′,4a’,9a’-tetrahydro-1’H,9’H-spiro[indoline-3,4′-xanthene]-3′-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCascade reaction
Michael Addition, (E)-1-(4-chlorophenyl)-3-phenylprop-2-en-1-one, ((nitromethyl)sulfonyl)benzene, (3R)-1-(4-chlorophenyl)-4-nitro-3-phenyl-4-(phenylsulfonyl)butan-1-one, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeMichael, Michael Addition
Cascade reaction, 3-Aminooxindoles, Isatin-Derived β,γ-Unsaturated α-Keto Esters, 3,3′-Pyrrolidinyl-bispirooxindoles, 3-[[(8α,9S)-10,11-Dihydrocinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Dihydrocinchonidine DerivativeCascade reaction
Cascade reaction, enynones, pyrazolones, pyranopyrazolones, (8α,9R)-6′-[[Tris(1-methylethyl)silyl]oxy]cinchonan-9-ol, Cupreine DerivativeCascade reaction
Intramolecular aza-Wacker oxidation cyclization, aromatic nitrogen‐containing dienes, dihydroindole nitrogen‐ containing polycyclic compounds, (9S)-2′-[(4S)-4-(1,1-Dimethylethyl)-4,5-dihydro-2-oxazolyl]-9-methoxycinchonan, Cinchonine DerivativeCyclization, Further Cyclizations, Further reactions, Intramolecular aza-Wacker oxidation cyclization, Intramolecular cyclization
Intramolecular aza-Wacker oxidation cyclization, N-(2-cinnamylphenyl)acrylamide, (1S,9aR)-2-methylene-1-phenyl-1,2,9,9a-tetrahydro-3H-pyrrolo[1,2-a]indol-3-one, (8α,9R)-2′-[(4S)-4-(1,1-Dimethylethyl)-4,5-dihydro-2-oxazolyl]-9-methoxycinchonan, Cinchonidine DerivativeCyclization, Further Cyclizations, Intramolecular aza-Wacker oxidation cyclization, Intramolecular cyclization