Epoxidation, (E)-4,4,4-trifluoro-1,3-diphenylbut-2-en-1-one, 2-isopropoxypropane, phenyl((2S,3S)-3-phenyl-3-(trifluoromethyl)oxiran-2-yl)methanone, 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinidine DerivativeEpoxidation Chlorination, (E)-3-phenylprop-2-en-1-ol, 4-(Dichloroiodo)-1,1′-biphenyl, (2S,3R)-2,3-dichloro-3-phenylpropan-1-ol, (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeChlorination Amination, α,β-unsaturated acyl chlorides, azodicarboxylates, di-tert-butyl (S)-3-oxo-3,5,6,7,8,8a-hexahydrocinnoline-1,2-dicarboxylate, (9S)-6′-methoxy-9-[(trimethylsilyl)oxy]-cinchonan hydrochloride, Quinidine DerivativeAmination Aldol reaction, 1-Methylisatin, ((2,2-difluoro-1-phenylvinyl)oxy)trimethylsilane, 3-difluoroalkyl 3-hydroxyoxindoles, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-urea, Quinidine DerivativeAldol, Aldol Michael Addition, tert-butyl (E)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-2-methylbenzoate, nitromethane, tert-butyl (R)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-(nitromethyl)butanoyl)-2-methylbenzoate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeMichael, Michael Addition Michael Addition, beta,beta-disubstituted enones, nitromethane, substituted 4,4,4-trifluoro-3-(nitromethyl)butanoyl, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael, Michael Addition Spirocyclization, 2-pyrones, substituted trifluoroethylisatin ketimines, substituted tricycle-fused dispirooxindoles, Dihydroquinine BaseCascade reaction, Spirocyclization Cyanation, substituted (E)-4,4,4-trifluorobut-2-enoyl, 2-hydroxy-2-methylpropanenitrile, substituted (R)-3-cyano-4,4,4-trifluorobutanoyl, (9S)-1-[[2,5-bis(trifluoromethyl)phenyl]methyl]-6′,9-dimethoxy-cinchonanium bromide, Quinidine DerivativeCyanation, Michael, Michael Addition Amination, 5,7-dimethyl-3-phenylindolin-2-one, di‐tert‐butyl azodicarboxylate, di-tert-butyl (S)-1-(5,7-dimethyl-2-oxo-3-phenylindolin-3-yl)hydrazine-1,2-dicarboxylate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9S)-6′-methoxycinchonan-9-yl]-thiourea, Quinidine Derivativealpha-Amination, Amination Desymmetrization, 4-hydroxy-4-methyldihydro-2H-pyran-2,6(3H)-dione, (R)-2-(2-methyl-4-oxooxetan-2-yl)acetic acid, Dihydroquinine BaseDesymmetrization« Older EntriesNext Entries »
Epoxidation, (E)-4,4,4-trifluoro-1,3-diphenylbut-2-en-1-one, 2-isopropoxypropane, phenyl((2S,3S)-3-phenyl-3-(trifluoromethyl)oxiran-2-yl)methanone, 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinidine DerivativeEpoxidation
Chlorination, (E)-3-phenylprop-2-en-1-ol, 4-(Dichloroiodo)-1,1′-biphenyl, (2S,3R)-2,3-dichloro-3-phenylpropan-1-ol, (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeChlorination
Amination, α,β-unsaturated acyl chlorides, azodicarboxylates, di-tert-butyl (S)-3-oxo-3,5,6,7,8,8a-hexahydrocinnoline-1,2-dicarboxylate, (9S)-6′-methoxy-9-[(trimethylsilyl)oxy]-cinchonan hydrochloride, Quinidine DerivativeAmination
Aldol reaction, 1-Methylisatin, ((2,2-difluoro-1-phenylvinyl)oxy)trimethylsilane, 3-difluoroalkyl 3-hydroxyoxindoles, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-urea, Quinidine DerivativeAldol, Aldol
Michael Addition, tert-butyl (E)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-2-methylbenzoate, nitromethane, tert-butyl (R)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-(nitromethyl)butanoyl)-2-methylbenzoate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeMichael, Michael Addition
Michael Addition, beta,beta-disubstituted enones, nitromethane, substituted 4,4,4-trifluoro-3-(nitromethyl)butanoyl, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael, Michael Addition
Spirocyclization, 2-pyrones, substituted trifluoroethylisatin ketimines, substituted tricycle-fused dispirooxindoles, Dihydroquinine BaseCascade reaction, Spirocyclization
Cyanation, substituted (E)-4,4,4-trifluorobut-2-enoyl, 2-hydroxy-2-methylpropanenitrile, substituted (R)-3-cyano-4,4,4-trifluorobutanoyl, (9S)-1-[[2,5-bis(trifluoromethyl)phenyl]methyl]-6′,9-dimethoxy-cinchonanium bromide, Quinidine DerivativeCyanation, Michael, Michael Addition
Amination, 5,7-dimethyl-3-phenylindolin-2-one, di‐tert‐butyl azodicarboxylate, di-tert-butyl (S)-1-(5,7-dimethyl-2-oxo-3-phenylindolin-3-yl)hydrazine-1,2-dicarboxylate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9S)-6′-methoxycinchonan-9-yl]-thiourea, Quinidine Derivativealpha-Amination, Amination
Desymmetrization, 4-hydroxy-4-methyldihydro-2H-pyran-2,6(3H)-dione, (R)-2-(2-methyl-4-oxooxetan-2-yl)acetic acid, Dihydroquinine BaseDesymmetrization