[10+2] Cycloaddition, 2‐alkylidene‐1‐indanones, activated alkenes, ethyl (1S,2S,3S,3aR,8aS)-1′-methyl-6-nitro-2′,8-dioxo-1-phenyl-3,3a,8,8a-tetrahydro-1H-spiro[cyclopenta[a]indene-2,3′-indoline]-3-carboxylate, 9-hydroxy-6′-methoxy-1-[[2,4,6-tris(1-methylethyl)phenyl]methyl]-cinchonanium bromide, Quinidine DerivativeCyclization, Cycloaddition Aldol reaction, substituted indoline-2,3-dione, methylketones, 3‐alkyl‐3‐hydroxyindolin‐2‐ones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeAldol, Aldol Mannich reaction, substituted ((phenylsulfonyl)methyl)carbamate, dibenzyl malonate, substituted dibenzyl 2-((methoxycarbonyl)amino)malonate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMannich, Mannich Michael Addition, S-methyl 2-cyanopropanethioate, 2-chloroacrylonitrile, S-methyl (2R,4R)-4-chloro-2,4-dicyano-2-methylbutanethioate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael, Michael Addition Desymmetrization, (3aR,7aS)-hexahydroisobenzofuran-1,3-dione, 2,2,2-trifluoroethan-1-ol, (1R,2S)-2-((2,2,2-trifluoroethoxy)carbonyl)cyclohexane-1-carboxylic acid, 2-[[(9S)-6′-methoxycinchonan-9-yl]oxy]-acetic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, Quinidine DerivativeDesymmetrization Michael Addition, beta,beta-disubstituted enones, nitromethane, 1,3-disubstituted (R)-4,4,4-trifluoro-3-(nitromethyl)-butan-1-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael, Michael Addition Michael Addition, (E)-7-oxo-7-phenylhept-5-enal, (E)-(2-nitrovinyl)benzene, (1R,2S,3R,4R)-3-nitro-4-(2-oxo-2-phenylethyl)-2-phenylcyclohexane-1-carbaldehyde, L-proline, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations, Michael, Michael Addition Michael Addition, trans-β-nitrostyrene, pentane-2,4-dione, (S)-3-(2-nitro-1-phenylethyl)pentane-2,4-dione, 3-(((S)-((1S,2S,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methyl)amino)-4-((((S)-2′-methyl-[1,1′-binaphthalen]-2-yl)methyl)amino)cyclobut-3-ene-1,2-dithione, Dihydroquinine DerivativeMichael, Michael Addition Michael Addition, butanone, (E)-(2-nitrovinyl)benzene, (3R,4S)-3-methyl-5-nitro-4-phenylpentan-2-one, L-proline, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael, Michael Addition Michael Addition, trans-β-nitrostyrene, pentane-2,4-dione, (S)-3-(2-nitro-1-phenylethyl)pentane-2,4-dione, 3-(((1S)-((2S,4S,5R)-5-Ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methyl)amino)-4-(R)-(((2′-methyl-[1,1′-binaphthalen]-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione, Dihydroquinine DerivativeMichael, Michael Addition« Older EntriesNext Entries »
[10+2] Cycloaddition, 2‐alkylidene‐1‐indanones, activated alkenes, ethyl (1S,2S,3S,3aR,8aS)-1′-methyl-6-nitro-2′,8-dioxo-1-phenyl-3,3a,8,8a-tetrahydro-1H-spiro[cyclopenta[a]indene-2,3′-indoline]-3-carboxylate, 9-hydroxy-6′-methoxy-1-[[2,4,6-tris(1-methylethyl)phenyl]methyl]-cinchonanium bromide, Quinidine DerivativeCyclization, Cycloaddition
Aldol reaction, substituted indoline-2,3-dione, methylketones, 3‐alkyl‐3‐hydroxyindolin‐2‐ones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeAldol, Aldol
Mannich reaction, substituted ((phenylsulfonyl)methyl)carbamate, dibenzyl malonate, substituted dibenzyl 2-((methoxycarbonyl)amino)malonate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMannich, Mannich
Michael Addition, S-methyl 2-cyanopropanethioate, 2-chloroacrylonitrile, S-methyl (2R,4R)-4-chloro-2,4-dicyano-2-methylbutanethioate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael, Michael Addition
Desymmetrization, (3aR,7aS)-hexahydroisobenzofuran-1,3-dione, 2,2,2-trifluoroethan-1-ol, (1R,2S)-2-((2,2,2-trifluoroethoxy)carbonyl)cyclohexane-1-carboxylic acid, 2-[[(9S)-6′-methoxycinchonan-9-yl]oxy]-acetic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, Quinidine DerivativeDesymmetrization
Michael Addition, beta,beta-disubstituted enones, nitromethane, 1,3-disubstituted (R)-4,4,4-trifluoro-3-(nitromethyl)-butan-1-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael, Michael Addition
Michael Addition, (E)-7-oxo-7-phenylhept-5-enal, (E)-(2-nitrovinyl)benzene, (1R,2S,3R,4R)-3-nitro-4-(2-oxo-2-phenylethyl)-2-phenylcyclohexane-1-carbaldehyde, L-proline, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations, Michael, Michael Addition
Michael Addition, trans-β-nitrostyrene, pentane-2,4-dione, (S)-3-(2-nitro-1-phenylethyl)pentane-2,4-dione, 3-(((S)-((1S,2S,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methyl)amino)-4-((((S)-2′-methyl-[1,1′-binaphthalen]-2-yl)methyl)amino)cyclobut-3-ene-1,2-dithione, Dihydroquinine DerivativeMichael, Michael Addition
Michael Addition, butanone, (E)-(2-nitrovinyl)benzene, (3R,4S)-3-methyl-5-nitro-4-phenylpentan-2-one, L-proline, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael, Michael Addition
Michael Addition, trans-β-nitrostyrene, pentane-2,4-dione, (S)-3-(2-nitro-1-phenylethyl)pentane-2,4-dione, 3-(((1S)-((2S,4S,5R)-5-Ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methyl)amino)-4-(R)-(((2′-methyl-[1,1′-binaphthalen]-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione, Dihydroquinine DerivativeMichael, Michael Addition