Fluorination/Semipinacol Rearrangement, 2-oxa allylic alcohols, N-fluorobenzenesulfonimide, β-fluoro ketones, (8α,9R)-(8′′α,9′′R)-9,9′′-[(2,5-Diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeFluorination, Fluorination, Semipinacol Rearrangement Arylation, quinones, azlactones, (R)-N-(3-benzyl-5-hydroxy-2-oxo-2,3-dihydronaphtho[1,2-b]furan-3-yl)benzamide, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations, Lactonization Spirocyclization, cyclic enones, (E)-3-styrylbenzo[d]isothiazole 1,1-dioxide, (3R,3’R,3a’S,6’R,6a’S)-3′,6′-diphenyl-2′,3′,3a’,5′,6′,6a’-hexahydro-2H,4’H-spiro[benzo[d]isothiazole-3,1′-pentalen]-4′-one 1,1-dioxide, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeSpirocyclization Sulfa-Michael, substituted 2-methylene-2,3-dihydro-1H-inden-1-one, 2-mercaptobenzaldehyde, substituted (2S,4’R)-4′-hydroxyspiro[indene-2,3′-thiochroman]-1(3H)-one, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeCascade reaction, Michael Addition, Sulfa-Michael, Sulfa-Michael Addition Aldol reaction, N,N-dibenzyl-3-(naphthalen-2-ylmethoxy)-2-oxopropanamide, 3-phenylpropanal, (3S,4R)-N,N-dibenzyl-4-hydroxy-3-(naphthalen-2-ylmethoxy)-2-oxo-6-phenylhexanamide, Phenylmethyl N-[(1S)-1-[[[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]carbonyl]amino]-2,2-dimethylpropyl]carbamate, Dihydroquinine DerivativeAldol, Aldol Diels-Alder reaction, 2-Pyrones, 2,5-Dienones, 7-substituted methyl (1R,8R)-3-oxo-8-((3-oxocyclohex-1-en-1-yl)methyl)-2-oxabicyclo[2.2.2]oct-5-ene-4-carboxylate, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeCycloaddition, Diels-Alder reaction Pictet-Sprengler, N-protected 2-(1H-indol-3-yl)ethan-1-amine, aldehydes, N-protected (1R)-substituted 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations Domino Michael Addition, quinones, azlactones, substituted (R)-N-(5-hydroxy-2-oxo-2,3-dihydronaphtho[1,2-b]furan-3-yl)formamide, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations, Lactonization, Michael, Michael Addition Spirocyclization, 3-substituted cyclopent-2-en-1-one, substituted 3-vinylbenzo[d]isothiazole 1,1-dioxide, substituted (3R,3a’S,6a’S)-2′,3′,3a’,6a’-tetrahydro-2H,4’H-spiro[benzo[d]isothiazole-3,1′-pentalen]-4′-one 1,1-dioxide, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeCascade reaction, Spirocyclization Spirocyclization, substituted (E)-2-ethylidene-2,3-dihydro-1H-inden-1-one, 2-mercaptobenzaldehyde, spirothiochromanones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeAldol, Aldol, Michael Addition, Spirocyclization, Sulfa-Michael« Older EntriesNext Entries »
Fluorination/Semipinacol Rearrangement, 2-oxa allylic alcohols, N-fluorobenzenesulfonimide, β-fluoro ketones, (8α,9R)-(8′′α,9′′R)-9,9′′-[(2,5-Diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeFluorination, Fluorination, Semipinacol Rearrangement
Arylation, quinones, azlactones, (R)-N-(3-benzyl-5-hydroxy-2-oxo-2,3-dihydronaphtho[1,2-b]furan-3-yl)benzamide, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations, Lactonization
Spirocyclization, cyclic enones, (E)-3-styrylbenzo[d]isothiazole 1,1-dioxide, (3R,3’R,3a’S,6’R,6a’S)-3′,6′-diphenyl-2′,3′,3a’,5′,6′,6a’-hexahydro-2H,4’H-spiro[benzo[d]isothiazole-3,1′-pentalen]-4′-one 1,1-dioxide, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeSpirocyclization
Sulfa-Michael, substituted 2-methylene-2,3-dihydro-1H-inden-1-one, 2-mercaptobenzaldehyde, substituted (2S,4’R)-4′-hydroxyspiro[indene-2,3′-thiochroman]-1(3H)-one, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeCascade reaction, Michael Addition, Sulfa-Michael, Sulfa-Michael Addition
Aldol reaction, N,N-dibenzyl-3-(naphthalen-2-ylmethoxy)-2-oxopropanamide, 3-phenylpropanal, (3S,4R)-N,N-dibenzyl-4-hydroxy-3-(naphthalen-2-ylmethoxy)-2-oxo-6-phenylhexanamide, Phenylmethyl N-[(1S)-1-[[[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]carbonyl]amino]-2,2-dimethylpropyl]carbamate, Dihydroquinine DerivativeAldol, Aldol
Diels-Alder reaction, 2-Pyrones, 2,5-Dienones, 7-substituted methyl (1R,8R)-3-oxo-8-((3-oxocyclohex-1-en-1-yl)methyl)-2-oxabicyclo[2.2.2]oct-5-ene-4-carboxylate, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeCycloaddition, Diels-Alder reaction
Pictet-Sprengler, N-protected 2-(1H-indol-3-yl)ethan-1-amine, aldehydes, N-protected (1R)-substituted 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations
Domino Michael Addition, quinones, azlactones, substituted (R)-N-(5-hydroxy-2-oxo-2,3-dihydronaphtho[1,2-b]furan-3-yl)formamide, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations, Lactonization, Michael, Michael Addition
Spirocyclization, 3-substituted cyclopent-2-en-1-one, substituted 3-vinylbenzo[d]isothiazole 1,1-dioxide, substituted (3R,3a’S,6a’S)-2′,3′,3a’,6a’-tetrahydro-2H,4’H-spiro[benzo[d]isothiazole-3,1′-pentalen]-4′-one 1,1-dioxide, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeCascade reaction, Spirocyclization
Spirocyclization, substituted (E)-2-ethylidene-2,3-dihydro-1H-inden-1-one, 2-mercaptobenzaldehyde, spirothiochromanones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeAldol, Aldol, Michael Addition, Spirocyclization, Sulfa-Michael