Umpolung, trifluoromethylketimines, α,β-unsaturated ketones, trifluoromethylated γ-amino esters, (9S)-1-(9-anthracenylmethyl)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-6′-(1-methylethoxy)-cinchonanium bromide, Cupreidine DerivativeFurther reactions, Umpolung Isomerization, cyanoketimines, α‐tertiary aminonitriles, (9S)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-cinchonan-6′-ol, Cupreidine DerivativeIsomerization Fluorination, α-branched enals, N-fluoro-N-(phenylsulfonyl)benzenesulfonamide, (R,E)-2-fluoro-2-methyl-4-(p-tolyl)but-3-enal, (9R)-9-Aminocinchonan-6′-ol, Cupreidine Derivativealpha-Fluorination, Fluorination Peroxidation, (E)-(4-((trifluoromethyl)sulfonyl)but-3-en-1-yl)benzene, (2-hydroperoxypropan-2-yl)benzene, (S)-(2-((4-phenyl-1-((trifluoromethyl)sulfonyl)butan-2-yl)peroxy)propan-2-yl)benzene, (9S)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1- [[2′-(1,1-dimethylethoxy)[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]- 6′-hydroxy-Cinchonanium inner salt, Cupreidine DerivativeFurther reactions, Kinetic resolution, Peroxidation, Resolution Spirocyclization, substituted 3-aminocyclohex-2-en-1-one, substituted indoline-2,3-dione, malononitrile, tetrahydroquinolin-5-one-based spirooxindoles, (9R)-inchonan-6′,9-diol, Cupreidine DerivativeSpirocyclization Desymmetrization, (1R,4S,7S,8R)-7,8-bis((benzyloxy)methyl)-2,3-dioxabicyclo[2.2.2]oct-5-ene, γ-hydroxyenones, (9S)-9-acetate-cinchonan-6′,9-diol, Cupreidine DerivativeDesymmetrization Henry reaction, 4-(trifluoromethyl)benzaldehyde, nitroethane, 2-nitro-1-(4-(trifluoromethyl)phenyl)propan-1-ol, (9S)-9-(phenylmethoxy)-cinchonan-6′-ol, Cupreidine DerivativeHenry, Henry Mannich reaction, 3-(2-isothiocyanatoacetyl)oxazolidin-2-one, (E)-N-benzylidene-4-bromobenzenesulfonamide, α,β-diamino acid derivatives, (9S)-9-acetate-cinchonan-6′,9-diol, Cupreidine DerivativeMannich, Mannich Vinylogous Michael Addition, maleimides, γ-aryl-substituted deconjugated butenolides, chiral butenolides with adjacent quaternary and tertiary stereocenters, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Vinylogous Michael Addition Cascade reaction, 5-benzylidene-2,2-dimethyl-1,3-dioxane-4,6-dione, diethyl (E)-2-((5-bromo-2-hydroxybenzylidene)amino)malonate, diethyl (3S,3aR,9bS)-8-bromo-4-oxo-3-phenyl-1,3a,4,9b-tetrahydrochromeno[4,3-b]pyrrole-2,2(3H)-dicarboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction« Older EntriesNext Entries »
Umpolung, trifluoromethylketimines, α,β-unsaturated ketones, trifluoromethylated γ-amino esters, (9S)-1-(9-anthracenylmethyl)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-6′-(1-methylethoxy)-cinchonanium bromide, Cupreidine DerivativeFurther reactions, Umpolung
Isomerization, cyanoketimines, α‐tertiary aminonitriles, (9S)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-cinchonan-6′-ol, Cupreidine DerivativeIsomerization
Fluorination, α-branched enals, N-fluoro-N-(phenylsulfonyl)benzenesulfonamide, (R,E)-2-fluoro-2-methyl-4-(p-tolyl)but-3-enal, (9R)-9-Aminocinchonan-6′-ol, Cupreidine Derivativealpha-Fluorination, Fluorination
Peroxidation, (E)-(4-((trifluoromethyl)sulfonyl)but-3-en-1-yl)benzene, (2-hydroperoxypropan-2-yl)benzene, (S)-(2-((4-phenyl-1-((trifluoromethyl)sulfonyl)butan-2-yl)peroxy)propan-2-yl)benzene, (9S)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1- [[2′-(1,1-dimethylethoxy)[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]- 6′-hydroxy-Cinchonanium inner salt, Cupreidine DerivativeFurther reactions, Kinetic resolution, Peroxidation, Resolution
Spirocyclization, substituted 3-aminocyclohex-2-en-1-one, substituted indoline-2,3-dione, malononitrile, tetrahydroquinolin-5-one-based spirooxindoles, (9R)-inchonan-6′,9-diol, Cupreidine DerivativeSpirocyclization
Desymmetrization, (1R,4S,7S,8R)-7,8-bis((benzyloxy)methyl)-2,3-dioxabicyclo[2.2.2]oct-5-ene, γ-hydroxyenones, (9S)-9-acetate-cinchonan-6′,9-diol, Cupreidine DerivativeDesymmetrization
Henry reaction, 4-(trifluoromethyl)benzaldehyde, nitroethane, 2-nitro-1-(4-(trifluoromethyl)phenyl)propan-1-ol, (9S)-9-(phenylmethoxy)-cinchonan-6′-ol, Cupreidine DerivativeHenry, Henry
Mannich reaction, 3-(2-isothiocyanatoacetyl)oxazolidin-2-one, (E)-N-benzylidene-4-bromobenzenesulfonamide, α,β-diamino acid derivatives, (9S)-9-acetate-cinchonan-6′,9-diol, Cupreidine DerivativeMannich, Mannich
Vinylogous Michael Addition, maleimides, γ-aryl-substituted deconjugated butenolides, chiral butenolides with adjacent quaternary and tertiary stereocenters, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Vinylogous Michael Addition
Cascade reaction, 5-benzylidene-2,2-dimethyl-1,3-dioxane-4,6-dione, diethyl (E)-2-((5-bromo-2-hydroxybenzylidene)amino)malonate, diethyl (3S,3aR,9bS)-8-bromo-4-oxo-3-phenyl-1,3a,4,9b-tetrahydrochromeno[4,3-b]pyrrole-2,2(3H)-dicarboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction
