Henry reaction, 3-substituted isopropyl 3-bromo-2-oxopropanoate, nitromethane, (3R)-substituted isopropyl (2R)-3-bromo-2-hydroxy-2-(nitromethyl)propanoate, (9S)-9-(2-methylbenzoate)cinchonan-6′,9-diol, Cupreidine DerivativeHenry, Henry Allylic Alkylation, 6-chloro-4-methyl-2-oxo-2H-chromene-3-carbonitrile, methyl 2-(((tert-butoxycarbonyl)oxy)(phenyl)methyl)acrylate, methyl (R)-4-(6-chloro-3-cyano-2-oxo-2H-chromen-4-yl)-2-methylene-3-phenylbutanoate, (1S,1’S,3R,3’R,4S,4’S,6R,6’R)-6,6′-((1S,1’S)- ((2,5-diphenylpyrimidine-4,6-diyl)bis(oxy))bis ((6-methoxyquinolin-4-yl)methylene)) bis(3-ethylquinuclidine), Dihydroquinidine DerivativeAlkylation, Allylic Alkylation [4+2]-Cyclization, ethyl (Z)-2-acetyl-4-phenylbut-2-enoate, ethyl (Z)-3-hydroxy-2-((E)-styryl)but-2-enoate, (E)-(2-nitrovinyl)benzene, ethyl (1’S,2’S,5’R,6’S)-5′-hydroxy-5′-methyl-6′-nitro-1′,2′,5′,6′-tetrahydro-[1,1′:2′,1”-terphenyl]-4′-carboxylate, (8α,9R)-1-[(2-fluoro-3-methylphenyl)methyl]-10,11-dihydro-9-hydroxy-6′-methoxy-Cinchonanium bromide, Dihydroquinine Derivative[4+2]-Cycloaddition, Cascade reaction, Cycloaddition [2+1]-Cycloaddition, 5-alkenyl thiazolones, 3-chlorooxindoles, spirooxindole-fused spirothiazolones, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine Derivative[2+1]-Cycloaddition, Cycloaddition, Spirocyclization Spirocyclization, (E)-3-arylenechroman-4-one or (E)-2-arylideneindan-1-one derivatives, bromo(nitro)methane, nitro-spirocyclopropanes, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeCascade reaction, Spirocyclization Henry reaction, ethyl (E)-2-oxopent-3-enoate, nitromethane, ethyl (R,E)-2-hydroxy-2-(nitromethyl)pent-3-enoate, (9S)-cinchonan-6′,9-diol-9-benzoate, Cupreidine DerivativeHenry, Henry Alkylation, 1-(bromomethyl)-3,5-dimethoxybenzene, dimethyl 2-oxo-2,3-dihydro-1H-indene-1,3-dicarboxylate, dimethyl (S)-3-(3,5-dimethoxybenzyl)-2-oxoindoline-1,3-dicarboxylate, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[[3,5-bis(trifluoromethyl)phenyl]amino]carbonyl]amino]-2′-chloro-10,11-dihydro-6′-methoxy-Cinchonanium bromide, Dihydroquinine DerivativeAlkylation, Alkylation Spirocyclization, alkylidene oxindoles, nitroketones, spiro-cyclopentaneoxindoles, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCascade reaction, Spirocyclization Domino Annulation, substituted 2-isothiocyanato-2,3-dihydro-1H-inden-1-one, substituted tert-butyl ((2-hydroxyphenyl)(tosyl)methyl)carbamate, substituted tert-butyl ((4bS,10R,10aR)-13-thioxo-10H,11H-4b,10a-(epiminomethanoimino)indeno[1,2-b]chromen-10-yl)carbamate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCascade reaction, Cyclization, Cycloaddition Cascade reaction, substituted 2-isothiocyanato-2,3-dihydro-1H-inden-1-ones, substituted (E)-4-benzylidene-1-phenylpyrrolidine-2,3-diones, substituted (2R,3’R,4’S)-1”,3′-diphenyl-5′-thioxodispiro[indene-2,2′-pyrrolidine-4′,3”-pyrrolidine]-1,4”,5”(3H)-triones, (9R)-10,11-Dihydro-6′-methoxycinchonan-9-yl]amino]-4-[(4-nitrophenyl)amino]-4-[(4-nitrophenyl)amino]-3-Cyclobutene-1,2-dione, Dihydroquinidine DerivativeCascade reaction, Spirocyclization« Older EntriesNext Entries »
Henry reaction, 3-substituted isopropyl 3-bromo-2-oxopropanoate, nitromethane, (3R)-substituted isopropyl (2R)-3-bromo-2-hydroxy-2-(nitromethyl)propanoate, (9S)-9-(2-methylbenzoate)cinchonan-6′,9-diol, Cupreidine DerivativeHenry, Henry
Allylic Alkylation, 6-chloro-4-methyl-2-oxo-2H-chromene-3-carbonitrile, methyl 2-(((tert-butoxycarbonyl)oxy)(phenyl)methyl)acrylate, methyl (R)-4-(6-chloro-3-cyano-2-oxo-2H-chromen-4-yl)-2-methylene-3-phenylbutanoate, (1S,1’S,3R,3’R,4S,4’S,6R,6’R)-6,6′-((1S,1’S)- ((2,5-diphenylpyrimidine-4,6-diyl)bis(oxy))bis ((6-methoxyquinolin-4-yl)methylene)) bis(3-ethylquinuclidine), Dihydroquinidine DerivativeAlkylation, Allylic Alkylation
[4+2]-Cyclization, ethyl (Z)-2-acetyl-4-phenylbut-2-enoate, ethyl (Z)-3-hydroxy-2-((E)-styryl)but-2-enoate, (E)-(2-nitrovinyl)benzene, ethyl (1’S,2’S,5’R,6’S)-5′-hydroxy-5′-methyl-6′-nitro-1′,2′,5′,6′-tetrahydro-[1,1′:2′,1”-terphenyl]-4′-carboxylate, (8α,9R)-1-[(2-fluoro-3-methylphenyl)methyl]-10,11-dihydro-9-hydroxy-6′-methoxy-Cinchonanium bromide, Dihydroquinine Derivative[4+2]-Cycloaddition, Cascade reaction, Cycloaddition
[2+1]-Cycloaddition, 5-alkenyl thiazolones, 3-chlorooxindoles, spirooxindole-fused spirothiazolones, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine Derivative[2+1]-Cycloaddition, Cycloaddition, Spirocyclization
Spirocyclization, (E)-3-arylenechroman-4-one or (E)-2-arylideneindan-1-one derivatives, bromo(nitro)methane, nitro-spirocyclopropanes, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeCascade reaction, Spirocyclization
Henry reaction, ethyl (E)-2-oxopent-3-enoate, nitromethane, ethyl (R,E)-2-hydroxy-2-(nitromethyl)pent-3-enoate, (9S)-cinchonan-6′,9-diol-9-benzoate, Cupreidine DerivativeHenry, Henry
Alkylation, 1-(bromomethyl)-3,5-dimethoxybenzene, dimethyl 2-oxo-2,3-dihydro-1H-indene-1,3-dicarboxylate, dimethyl (S)-3-(3,5-dimethoxybenzyl)-2-oxoindoline-1,3-dicarboxylate, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[[3,5-bis(trifluoromethyl)phenyl]amino]carbonyl]amino]-2′-chloro-10,11-dihydro-6′-methoxy-Cinchonanium bromide, Dihydroquinine DerivativeAlkylation, Alkylation
Spirocyclization, alkylidene oxindoles, nitroketones, spiro-cyclopentaneoxindoles, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCascade reaction, Spirocyclization
Domino Annulation, substituted 2-isothiocyanato-2,3-dihydro-1H-inden-1-one, substituted tert-butyl ((2-hydroxyphenyl)(tosyl)methyl)carbamate, substituted tert-butyl ((4bS,10R,10aR)-13-thioxo-10H,11H-4b,10a-(epiminomethanoimino)indeno[1,2-b]chromen-10-yl)carbamate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCascade reaction, Cyclization, Cycloaddition
Cascade reaction, substituted 2-isothiocyanato-2,3-dihydro-1H-inden-1-ones, substituted (E)-4-benzylidene-1-phenylpyrrolidine-2,3-diones, substituted (2R,3’R,4’S)-1”,3′-diphenyl-5′-thioxodispiro[indene-2,2′-pyrrolidine-4′,3”-pyrrolidine]-1,4”,5”(3H)-triones, (9R)-10,11-Dihydro-6′-methoxycinchonan-9-yl]amino]-4-[(4-nitrophenyl)amino]-4-[(4-nitrophenyl)amino]-3-Cyclobutene-1,2-dione, Dihydroquinidine DerivativeCascade reaction, Spirocyclization