Mannich reaction, imines, dithiomalonates, S,S-dibenzyl (S)-2-(((tert-butoxycarbonyl)amino)(phenyl)methyl)propanebis(thioate), 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich Cyclization, substituted 1-benzylquinolin-1-ium, substituted (E)-4-(2-hydroxyphenyl)but-3-en-2-one, substituted (3aS,3a1R,8aS,13bR)-9-benzyl-3,3a,3a1,8a,9,13b-hexahydrochromeno[2,3,4-gh]phenanthridin-2(1H)-one, mandelic acid, 3-methyl-D-Valine (9S)-6′-methoxycinchonan-9-yl ester, Quinine DerivativeCascade reaction, Cyclization, Cyclization, Further Cyclizations Mannich reaction, α-ketoamides, p-nosylimines, substituted 3-hydroxy-4-((4-nitrophenyl)sulfonamido)-2-oxobutanamide, N-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-N-(phenylmethyl)-5-(trifluoromethyl)-benzamide, Quinine DerivativeMannich, Mannich Aldol reaction, 4-fluoroisatin, 3-(4-chlorophenyl)-2,2-difluoro-3-oxopropanoic acid, (S)-3-(2-(4-chlorophenyl)-1,1-difluoro-2-oxoethyl)-4-fluoro-3-hydroxyindolin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeAldol, Aldol Aldol reaction, 4-nitrobenzaldehyde, 2-fluoro-3-((4-methoxyphenyl)thio)-3-oxopropanoic acid, S-(4-methoxyphenyl) (2S,3S)-2-fluoro-3-hydroxy-3-(4-nitrophenyl)propanethioate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeAldol, Aldol Spirocyclization, ethyl 3-oxobutanoate, (E)-(2-nitrovinyl)benzene, (Z)-4-benzylidene-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, spiropyrazolones, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization Spirocyclization, substituted indoline-2,3-dione, malononitrile, substituted 2-hydroxynaphthalene-1,4-dione, chiral pyranonaphthoquinone‐fused spirooxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeSpirocyclization Spirocyclization, 2-Isothiocyanato-1-indanones, substituted 3-iminoindolin-2-one, substituted (2S,5’R)-2′-thioxodispiro[indene-2,4′-imidazolidine-5′,3”-indoline]-1,2”(3H)-dione, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization Spirocyclization, rhodanine derivatives, N-(2,2,2-trifluoroethyl) isatin ketimines, bispiro [oxindole-pyrrolidine-rhodanine]s, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization Spirocyclization, ketones, substituted 3-vinylbenzo[d]isothiazole 1,1-dioxide, substituted (S)-2H-spiro[benzo[d]isothiazole-3,1′-cyclohexan]-3′-one 1,1-dioxide, salicylic acid, (8α,9R)-6′-Methoxycinchonan-9-amine, Quinine DerivativeSpirocyclization« Older EntriesNext Entries »
Mannich reaction, imines, dithiomalonates, S,S-dibenzyl (S)-2-(((tert-butoxycarbonyl)amino)(phenyl)methyl)propanebis(thioate), 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich
Cyclization, substituted 1-benzylquinolin-1-ium, substituted (E)-4-(2-hydroxyphenyl)but-3-en-2-one, substituted (3aS,3a1R,8aS,13bR)-9-benzyl-3,3a,3a1,8a,9,13b-hexahydrochromeno[2,3,4-gh]phenanthridin-2(1H)-one, mandelic acid, 3-methyl-D-Valine (9S)-6′-methoxycinchonan-9-yl ester, Quinine DerivativeCascade reaction, Cyclization, Cyclization, Further Cyclizations
Mannich reaction, α-ketoamides, p-nosylimines, substituted 3-hydroxy-4-((4-nitrophenyl)sulfonamido)-2-oxobutanamide, N-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-N-(phenylmethyl)-5-(trifluoromethyl)-benzamide, Quinine DerivativeMannich, Mannich
Aldol reaction, 4-fluoroisatin, 3-(4-chlorophenyl)-2,2-difluoro-3-oxopropanoic acid, (S)-3-(2-(4-chlorophenyl)-1,1-difluoro-2-oxoethyl)-4-fluoro-3-hydroxyindolin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeAldol, Aldol
Aldol reaction, 4-nitrobenzaldehyde, 2-fluoro-3-((4-methoxyphenyl)thio)-3-oxopropanoic acid, S-(4-methoxyphenyl) (2S,3S)-2-fluoro-3-hydroxy-3-(4-nitrophenyl)propanethioate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeAldol, Aldol
Spirocyclization, ethyl 3-oxobutanoate, (E)-(2-nitrovinyl)benzene, (Z)-4-benzylidene-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, spiropyrazolones, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization
Spirocyclization, substituted indoline-2,3-dione, malononitrile, substituted 2-hydroxynaphthalene-1,4-dione, chiral pyranonaphthoquinone‐fused spirooxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeSpirocyclization
Spirocyclization, 2-Isothiocyanato-1-indanones, substituted 3-iminoindolin-2-one, substituted (2S,5’R)-2′-thioxodispiro[indene-2,4′-imidazolidine-5′,3”-indoline]-1,2”(3H)-dione, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization
Spirocyclization, rhodanine derivatives, N-(2,2,2-trifluoroethyl) isatin ketimines, bispiro [oxindole-pyrrolidine-rhodanine]s, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization
Spirocyclization, ketones, substituted 3-vinylbenzo[d]isothiazole 1,1-dioxide, substituted (S)-2H-spiro[benzo[d]isothiazole-3,1′-cyclohexan]-3′-one 1,1-dioxide, salicylic acid, (8α,9R)-6′-Methoxycinchonan-9-amine, Quinine DerivativeSpirocyclization
