Addition, aromatic aldehydes, diethylzinc, substituted (S)-1-phenylpropan-1-ol, (R)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl 2-(((Z)-3,5-di-tert-butyl-2-hydroxybenzylidene)amino)acetate, Quinine DerivativeAddition Intramolecular Michael Addition, phenyl-keto-enones, 2,3-disubstituted cis-2,3-dihydrobenzofurans, (R)-mandelic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeCyclization, Further Cyclizations, Intramolecular cyclization, Michael, Michael Addition Cycloannulation, Isocyanoacetates, alkynyl ketones, axially chiral 3‐Arylpyrroles, silver oxide, 2-(diphenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine Derivative[3+2] Annulation, Atropisomer synthesis, Cyclization, Further Cyclizations Domino Michael, α-nitroketones, γ/δ-hydroxyenones, ß-nitro-γ/δ-hydroxyketones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition Mannich reaction, dihydro‐3‐carboalkoxy‐2‐quinolones, tert-butyloxycarbonyl protected imines, substituted (S)-3-(((tert-butoxycarbonyl)amino)methyl)-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative Aza-Henry (Nitro-Mannich), substituted 3H-indole, nitroalkanes, substituted (R)-2-(nitromethyl)indoline, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Spirocyclization, 2-methoxy-6-(phenyl(tosyl)methyl)phenol, 4-bromo-2-(3-bromophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one, spirobenzofuranpyrazolones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization Pictet-Sprengler, 2-(1H-indol-3-yl)-N-(naphthalen-2-ylmethyl)ethan-1-amine, benzaldehyde, (R)-2-(naphthalen-2-ylmethyl)-1-phenyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCyclization, Further Cyclizations, Pictet-Spengler Reaction Mannich reaction, pyrazolamides, cyclic trifluoromethylketimines, (S)-6-chloro-1-(4-methoxybenzyl)-4-((S)-2-oxo-2-(1H-pyrazol-1-yl)-1-(p-tolyl)ethyl)-4-(trifluoromethyl)-3,4-dihydroquinazolin-2(1H)-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich Mannich reaction, 5-(4-chlorophenyl)-1,3,4-thiadiazol-2-amine, 2,3-dichlorobenzaldehyde, diethyl malonate, diethyl 2-(((5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl)amino)(2,3-dichlorophenyl)-l3-methyl)malonate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich« Older EntriesNext Entries »
Addition, aromatic aldehydes, diethylzinc, substituted (S)-1-phenylpropan-1-ol, (R)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl 2-(((Z)-3,5-di-tert-butyl-2-hydroxybenzylidene)amino)acetate, Quinine DerivativeAddition
Intramolecular Michael Addition, phenyl-keto-enones, 2,3-disubstituted cis-2,3-dihydrobenzofurans, (R)-mandelic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeCyclization, Further Cyclizations, Intramolecular cyclization, Michael, Michael Addition
Cycloannulation, Isocyanoacetates, alkynyl ketones, axially chiral 3‐Arylpyrroles, silver oxide, 2-(diphenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine Derivative[3+2] Annulation, Atropisomer synthesis, Cyclization, Further Cyclizations
Domino Michael, α-nitroketones, γ/δ-hydroxyenones, ß-nitro-γ/δ-hydroxyketones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
Mannich reaction, dihydro‐3‐carboalkoxy‐2‐quinolones, tert-butyloxycarbonyl protected imines, substituted (S)-3-(((tert-butoxycarbonyl)amino)methyl)-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative
Aza-Henry (Nitro-Mannich), substituted 3H-indole, nitroalkanes, substituted (R)-2-(nitromethyl)indoline, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Spirocyclization, 2-methoxy-6-(phenyl(tosyl)methyl)phenol, 4-bromo-2-(3-bromophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one, spirobenzofuranpyrazolones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization
Pictet-Sprengler, 2-(1H-indol-3-yl)-N-(naphthalen-2-ylmethyl)ethan-1-amine, benzaldehyde, (R)-2-(naphthalen-2-ylmethyl)-1-phenyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCyclization, Further Cyclizations, Pictet-Spengler Reaction
Mannich reaction, pyrazolamides, cyclic trifluoromethylketimines, (S)-6-chloro-1-(4-methoxybenzyl)-4-((S)-2-oxo-2-(1H-pyrazol-1-yl)-1-(p-tolyl)ethyl)-4-(trifluoromethyl)-3,4-dihydroquinazolin-2(1H)-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich
Mannich reaction, 5-(4-chlorophenyl)-1,3,4-thiadiazol-2-amine, 2,3-dichlorobenzaldehyde, diethyl malonate, diethyl 2-(((5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl)amino)(2,3-dichlorophenyl)-l3-methyl)malonate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich
