Bromolactonization, cyclohexadienes, N-bromsuccinimid, (3aS)-substituted (7S,7aS)-7-bromo-3a,6,7,7a-tetrahydrobenzofuran-2(3H)-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeBromination, Desymmetrization, Lactonization Bromolactonization, 5-phenylhex-5-enoic acid, N-bromsuccinimid, (S)-6-(bromomethyl)-6-phenyltetrahydro-2H-pyran-2-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeBromination, Lactonization Chlorination, substituted 4-phenylpent-4-enoic acid, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, substituted (R)-5-(chloromethyl)-5-phenyldihydrofuran-2(3H)-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Lactonization Dithiotrifluoromethylthiolation, (3s,5s,7s)-adamantan-1-yl 5-methoxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, 2-((trifluoromethyl)sulfinothioyl)isoindoline-1,3-dione, (3S,5S,7S)-adamantan-1-yl (R)-5-methoxy-1-oxo-2-((S)-(trifluoromethyl)sulfinothioyl)-2,3-dihydro-1H-indene-2-carboxylate, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeTrifluoro-methylthiolation Trifluoromethylthiolation, 3-substituted oxindoles, [(trifluoromethyl)thio]-silver, (S)-5-chloro-3-(4-chlorophenyl)-3-((trifluoromethyl)thio)indolin-2-one, 1,3,5-Trichloroisocyanuric acid, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeTrifluoro-methylthiolation Sulfenylation, 3-aryloxindoles, 1-(benzylthio)-1H-pyrrole-2,5-dione, (S)-1-benzyl-3-(benzylthio)-5-chloro-3-phenylindolin-2-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeSulfenylation Desymmetrization, 2-acetylcyclopentan-1-one, 1-(2-(tert-butyl)phenyl)-1H-pyrrole-2,5-dione, (R)-3-((S)-1-acetyl-2-oxocyclopentyl)-1-(2-(tert-butyl)phenyl)pyrrolidine-2,5-dione, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeAtropisomer synthesis, Desymmetrization Desymmetrization, cyclic anhydrides, methanol, (2R,3S)-4-methoxy-2,3-dimethyl-4-oxobutanoic acid, 1,4-Bis[(9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-9,10-anthracenedione, Dihydroquinidine DerivativeDesymmetrization Desymmetrization, cyclic anhydrides, methanol, (2R,3S)-4-methoxy-2,3-dimethyl-4-oxobutanoic acid, 1,4-Bis[(9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-9,10-anthracenedione, Dihydroquinidine DerivativeDesymmetrization Chlorination, substituted 1-(1-phenylvinyl)cyclobutan-1-ol, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, substituted (S)-2-(chloromethyl)-2-phenylcyclopentan-1-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Further reactions, Rearrangement« Older EntriesNext Entries »
Bromolactonization, cyclohexadienes, N-bromsuccinimid, (3aS)-substituted (7S,7aS)-7-bromo-3a,6,7,7a-tetrahydrobenzofuran-2(3H)-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeBromination, Desymmetrization, Lactonization
Bromolactonization, 5-phenylhex-5-enoic acid, N-bromsuccinimid, (S)-6-(bromomethyl)-6-phenyltetrahydro-2H-pyran-2-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeBromination, Lactonization
Chlorination, substituted 4-phenylpent-4-enoic acid, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, substituted (R)-5-(chloromethyl)-5-phenyldihydrofuran-2(3H)-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Lactonization
Dithiotrifluoromethylthiolation, (3s,5s,7s)-adamantan-1-yl 5-methoxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, 2-((trifluoromethyl)sulfinothioyl)isoindoline-1,3-dione, (3S,5S,7S)-adamantan-1-yl (R)-5-methoxy-1-oxo-2-((S)-(trifluoromethyl)sulfinothioyl)-2,3-dihydro-1H-indene-2-carboxylate, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeTrifluoro-methylthiolation
Trifluoromethylthiolation, 3-substituted oxindoles, [(trifluoromethyl)thio]-silver, (S)-5-chloro-3-(4-chlorophenyl)-3-((trifluoromethyl)thio)indolin-2-one, 1,3,5-Trichloroisocyanuric acid, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeTrifluoro-methylthiolation
Sulfenylation, 3-aryloxindoles, 1-(benzylthio)-1H-pyrrole-2,5-dione, (S)-1-benzyl-3-(benzylthio)-5-chloro-3-phenylindolin-2-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeSulfenylation
Desymmetrization, 2-acetylcyclopentan-1-one, 1-(2-(tert-butyl)phenyl)-1H-pyrrole-2,5-dione, (R)-3-((S)-1-acetyl-2-oxocyclopentyl)-1-(2-(tert-butyl)phenyl)pyrrolidine-2,5-dione, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeAtropisomer synthesis, Desymmetrization
Desymmetrization, cyclic anhydrides, methanol, (2R,3S)-4-methoxy-2,3-dimethyl-4-oxobutanoic acid, 1,4-Bis[(9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-9,10-anthracenedione, Dihydroquinidine DerivativeDesymmetrization
Desymmetrization, cyclic anhydrides, methanol, (2R,3S)-4-methoxy-2,3-dimethyl-4-oxobutanoic acid, 1,4-Bis[(9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-9,10-anthracenedione, Dihydroquinidine DerivativeDesymmetrization
Chlorination, substituted 1-(1-phenylvinyl)cyclobutan-1-ol, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, substituted (S)-2-(chloromethyl)-2-phenylcyclopentan-1-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Further reactions, Rearrangement
