conjugate addition, isatin derived N-Cbz ketimines, monothiomalonates, chiral 3-substituted 3-amino-2-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylurea, Cinchonidine DerivativeAddition Trifluoromethylation, 4-bromo-2-(3-hydroxy-3-methylbutoxy)-9H-fluoren-9-one, (R)-4-bromo-2-(3-hydroxy-3-methylbutoxy)-9-(trifluoromethyl)-9H-fluoren-9-ol, 1-[[4-(1,1-dimethylethyl)-3-methoxyphenyl]methyl]-9-hydroxy-(8α,9R)-cinchonanium bromide, Cinchonidine DerivativeFluorination, Fluoromethylation, Trifluoromethylation Spirocyclization, dioxindoles, trans-α-cyano-α,β-unsaturated ketones, dihydrofuran-spirooxindoles, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonidine DerivativeSpirocyclization Addition of Thiols, trihalomethylaldimine, thiols, trihalomethylated N,S-acetals, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonidine DerivativeAddition Peroxidation of Ketimines, isatin derived N-Cbz ketimines, hydroperoxides, isatin derived a-amino-hydroperoxides, N-(8α,9S)-Cinchonan-9-yl-8-quinolinesulfonamide, Cinchonidine DerivativeFurther reactions, Peroxidation Addition of alcohols, substituted tert-butyl oxoindolin-3-ylidene carbamates, alcohols, isatin-derived N,O-aminals, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-2′-phenylcinchonan-9-yl]thiourea, Cinchonidine DerivativeAddition Friedel-Crafts Reaction, 2,2,2-trichloroacetaldehyde, 4-butoxy-3-methoxyphenol, (S)-4-butoxy-5-methoxy-2-(2,2,2-trichloro-1-hydroxyethyl)phenol, 3,5-dinitro-N-((S)-quinolin-4-yl((1S,2S,4S,5R)- 5-vinylquinuclidin-2-yl)methyl)benzamide, Cinchonidine DerivativeFriedel-Crafts, Friedel-Crafts reaction Michael Addition, β-nitrostyrenes, acetylacetone, substituted 3-nitroethyl-2,4-pentanedione, (9S)-(9′′S)-1,1′′-[[5,11,17,23-tetrakis(1,1-dimethylethyl)-26,28-dihydroxypentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3,5,7(28),9,11,13(27),15,17,19(26),21,23-dodecaene-25,27-diyl]bis(oxy-3,1-propanediyl)]bis[9-hydroxy-cinchonanium bromide, Cinchonidine DerivativeMichael, Michael Addition Spirocyclization, 3-hydroxyoxindoles, 3-fluoroethylidene oxindoles, spirooxindoles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Dihydroquinidine DerivativeCascade reaction, Spirocyclization Chlorination, indole derived benzamides, 1,3-Dichloro-5,5-diphenyl-2,4-imidazolidinedione, substituted 1-((3’S,4R)-3′-chlorospiro[benzo[d][1,3]oxazine-4,2′-indolin]-1′-yl)ethan-1-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Spirocyclization« Older EntriesNext Entries »
conjugate addition, isatin derived N-Cbz ketimines, monothiomalonates, chiral 3-substituted 3-amino-2-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylurea, Cinchonidine DerivativeAddition
Trifluoromethylation, 4-bromo-2-(3-hydroxy-3-methylbutoxy)-9H-fluoren-9-one, (R)-4-bromo-2-(3-hydroxy-3-methylbutoxy)-9-(trifluoromethyl)-9H-fluoren-9-ol, 1-[[4-(1,1-dimethylethyl)-3-methoxyphenyl]methyl]-9-hydroxy-(8α,9R)-cinchonanium bromide, Cinchonidine DerivativeFluorination, Fluoromethylation, Trifluoromethylation
Spirocyclization, dioxindoles, trans-α-cyano-α,β-unsaturated ketones, dihydrofuran-spirooxindoles, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonidine DerivativeSpirocyclization
Addition of Thiols, trihalomethylaldimine, thiols, trihalomethylated N,S-acetals, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonidine DerivativeAddition
Peroxidation of Ketimines, isatin derived N-Cbz ketimines, hydroperoxides, isatin derived a-amino-hydroperoxides, N-(8α,9S)-Cinchonan-9-yl-8-quinolinesulfonamide, Cinchonidine DerivativeFurther reactions, Peroxidation
Addition of alcohols, substituted tert-butyl oxoindolin-3-ylidene carbamates, alcohols, isatin-derived N,O-aminals, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-2′-phenylcinchonan-9-yl]thiourea, Cinchonidine DerivativeAddition
Friedel-Crafts Reaction, 2,2,2-trichloroacetaldehyde, 4-butoxy-3-methoxyphenol, (S)-4-butoxy-5-methoxy-2-(2,2,2-trichloro-1-hydroxyethyl)phenol, 3,5-dinitro-N-((S)-quinolin-4-yl((1S,2S,4S,5R)- 5-vinylquinuclidin-2-yl)methyl)benzamide, Cinchonidine DerivativeFriedel-Crafts, Friedel-Crafts reaction
Michael Addition, β-nitrostyrenes, acetylacetone, substituted 3-nitroethyl-2,4-pentanedione, (9S)-(9′′S)-1,1′′-[[5,11,17,23-tetrakis(1,1-dimethylethyl)-26,28-dihydroxypentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3,5,7(28),9,11,13(27),15,17,19(26),21,23-dodecaene-25,27-diyl]bis(oxy-3,1-propanediyl)]bis[9-hydroxy-cinchonanium bromide, Cinchonidine DerivativeMichael, Michael Addition
Spirocyclization, 3-hydroxyoxindoles, 3-fluoroethylidene oxindoles, spirooxindoles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Dihydroquinidine DerivativeCascade reaction, Spirocyclization
Chlorination, indole derived benzamides, 1,3-Dichloro-5,5-diphenyl-2,4-imidazolidinedione, substituted 1-((3’S,4R)-3′-chlorospiro[benzo[d][1,3]oxazine-4,2′-indolin]-1′-yl)ethan-1-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Spirocyclization
