Mannich reaction, unfunctionalized ketones, 4-methylbenzenesulfonamide, substituted benzaldehydes, substituted (S)-4-methyl-N-(3-oxo-1-phenylpropyl)benzenesulfonamide, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9S)-9-(phenylmethoxy)cinchonan-6′-yl]-thiourea, 6´-Aminocinchonine DerivativeMannich, Mannich Amination, 2,2,3,3,4,4,4-heptafluorobutyl sulfamate, 4-phenylbutan-1-ol, 2,2,3,3,4,4,4-heptafluorobutyl (R)-(4-hydroxy-1-phenylbutyl)sulfamate, ruthenium(II), (9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-10,11-dihydro-9-hydroxy-6′-methoxy-cinchonanium bromide, Dihydroquinidine DerivativeAmination Dihydroxylation, 1-methyl-4-vinylbenzene, (R)-1-(p-tolyl)ethane-1,2-diol, osmium(VIII) oxide, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeHydroxylation [4+4] Annulation, 1-azadienes, cyclobutenones, substituted (E)-1-tosyl-5,6-dihydrobenzofuro[3,2-b]azocin-2(1H)-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeCyclization, Cycloaddition Atropisomer synthesis, phosphamides, 2-(((tert-butoxycarbonyl)oxy)methyl)acrylates, axially chiral phosphamides, Dihydroquinidine BaseAtropisomer synthesis Strecker Synthesis, spiro[cyclohexane-1,3′-indole], ethyl carbonocyanidate, (S)-spiro[cyclohexane-1,3′-indoline]-2′-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeStrecker Isomerization, 5,5-dimethyl-3,4,5,6,7,8-hexahydronaphthalen-2(1H)-one, (S)-5,5-dimethyl-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one, (R)-2-chloropropanoic acid, N1-[(9R)-6′-methoxycinchonan-9-yl]-4-(trifluoromethyl)-1,2-benzenediamine, Quinidine DerivativeIsomerization Atropisomer Synthesis, β-sulfinyl esters, substituted naphthalen-2-ol, sulfone-based axially chiral styrenes, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4- [[(9R)-6′-methoxycinchonan-9-yl]amino]-3- cyclobutene-1,2-dione, Quinidine DerivativeAtropisomer synthesis Desymmetrization, diethyl 3-oxobicyclo[3.1.0]hexane-6,6-dicarboxylate, diethyl (S)-2-(4-oxocyclopent-2-en-1-yl)malonate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′- methoxycinchonan-9-yl]thiourea, Quinidine DerivativeDesymmetrization Michael Addition, β-trifluoromethylated acrylamides, nitromethane, (R)-4-benzyl-3-((R)-4,4,4-trifluoro-3-(nitromethyl)butanoyl)oxazolidin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′- methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael, Michael Addition« Older EntriesNext Entries »
Mannich reaction, unfunctionalized ketones, 4-methylbenzenesulfonamide, substituted benzaldehydes, substituted (S)-4-methyl-N-(3-oxo-1-phenylpropyl)benzenesulfonamide, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9S)-9-(phenylmethoxy)cinchonan-6′-yl]-thiourea, 6´-Aminocinchonine DerivativeMannich, Mannich
Amination, 2,2,3,3,4,4,4-heptafluorobutyl sulfamate, 4-phenylbutan-1-ol, 2,2,3,3,4,4,4-heptafluorobutyl (R)-(4-hydroxy-1-phenylbutyl)sulfamate, ruthenium(II), (9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-10,11-dihydro-9-hydroxy-6′-methoxy-cinchonanium bromide, Dihydroquinidine DerivativeAmination
Dihydroxylation, 1-methyl-4-vinylbenzene, (R)-1-(p-tolyl)ethane-1,2-diol, osmium(VIII) oxide, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeHydroxylation
[4+4] Annulation, 1-azadienes, cyclobutenones, substituted (E)-1-tosyl-5,6-dihydrobenzofuro[3,2-b]azocin-2(1H)-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeCyclization, Cycloaddition
Atropisomer synthesis, phosphamides, 2-(((tert-butoxycarbonyl)oxy)methyl)acrylates, axially chiral phosphamides, Dihydroquinidine BaseAtropisomer synthesis
Strecker Synthesis, spiro[cyclohexane-1,3′-indole], ethyl carbonocyanidate, (S)-spiro[cyclohexane-1,3′-indoline]-2′-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeStrecker
Isomerization, 5,5-dimethyl-3,4,5,6,7,8-hexahydronaphthalen-2(1H)-one, (S)-5,5-dimethyl-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one, (R)-2-chloropropanoic acid, N1-[(9R)-6′-methoxycinchonan-9-yl]-4-(trifluoromethyl)-1,2-benzenediamine, Quinidine DerivativeIsomerization
Atropisomer Synthesis, β-sulfinyl esters, substituted naphthalen-2-ol, sulfone-based axially chiral styrenes, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4- [[(9R)-6′-methoxycinchonan-9-yl]amino]-3- cyclobutene-1,2-dione, Quinidine DerivativeAtropisomer synthesis
Desymmetrization, diethyl 3-oxobicyclo[3.1.0]hexane-6,6-dicarboxylate, diethyl (S)-2-(4-oxocyclopent-2-en-1-yl)malonate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′- methoxycinchonan-9-yl]thiourea, Quinidine DerivativeDesymmetrization
Michael Addition, β-trifluoromethylated acrylamides, nitromethane, (R)-4-benzyl-3-((R)-4,4,4-trifluoro-3-(nitromethyl)butanoyl)oxazolidin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′- methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael, Michael Addition
