Aza-Michael Addition, vinyl sulfonamides, bicyclic δ‐sultams, (8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-amine, Dihydroquinine DerivativeAza-Michael, Intramolecular Aza-Michael, Michael Addition [3+2]-Annulation, substituted tert-butyl (3-cyano-1,1,1-trifluorobut-3-en-2-yl) carbonate, substituted benzo[d]isothiazole-3-carboxylate 1,1-dioxide, substituted (9bS)-2-cyano-1-(trifluoromethyl)benzo[d]pyrrolo[1,2-b]isothiazole-9b(1H)-carboxylate 5,5-dioxide, (8α,9R)-(8′′α,9′′R)-9,9′′-[(2,5-Diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine Derivative[3+2] Annulation, Cyclization, Further Cyclizations Amination, amides, α-diazoketones, chiral amides, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine Derivativealpha-Amination, Amination Cyclopropanation, oxindoles, α-chloro-β-diketones, substituted tert-butyl 2′-oxospiro[cyclopropane-1,3′-indoline]-1′-carboxylate, N-[2,6-bis(1-methylethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-thiourea, Dihydroquinine DerivativeCyclopropanation, Spirocyclization Cyclopropanation, oxindoles, bromonitroalkanes, substituted tert-butyl 2-nitro-2′-oxospiro[cyclopropane-1,3′-indoline]-1′-carboxylate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCyclopropanation, Spirocyclization Fluorination, 3-functionalized 2-oxindoles, N-fluorbenzolsulfonimid, 3-functionalized 3-fluoro-2-oxindoles, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-tricyclo[3.3.1.13,7]dec-1-yl-urea, Quinine DerivativeFluorination, Fluorination Aldol reaction, substituted 2-(benzylthio)-3,5-dihydro-4H-imidazol-4-one, pyridine 2-carbaldehyde N-oxides, substituted 2-((1S)-(2-(benzylthio)-5-oxo-4,5-dihydro-1H-imidazol-4-yl)(hydroxy)methyl)pyridine 1-oxide, N-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)-benzamide, Quinine DerivativeAldol, Aldol Cyclopropanation, 2-bromomalonates, substituted 4-methylene-2,4-dihydro-3H-pyrazol-3-one, spirocyclopropyl pyrazolones, 1,4-bis[[(8α,9R)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]oxy]-9,10-Anthracenedione, Dihydroquinine DerivativeCyclopropanation, Spirocyclization Hydrazination, 1,5-Dihydro-3-hydroxy-4-methyl-1-(1-naphthalenylmethyl)-2H-pyrrol-2-one, di-tert-butyl (E)-diazene-1,2-dicarboxylate, di-tert-butyl (R)-1-(3-methyl-1-(naphthalen-1-ylmethyl)-4,5-dioxopyrrolidin-3-yl)hydrazine-1,2-dicarboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-3-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)benzamide, N-[3,5-Bis(trifluoromethyl)phenyl]-3-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)benzamide, Quinine DerivativeFurther reactions, Hydrazination Michael Addition, α-monosubstituted β-tetralones, nitroolefins, α-disubstituted β-tetralones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition« Older EntriesNext Entries »
Aza-Michael Addition, vinyl sulfonamides, bicyclic δ‐sultams, (8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-amine, Dihydroquinine DerivativeAza-Michael, Intramolecular Aza-Michael, Michael Addition
[3+2]-Annulation, substituted tert-butyl (3-cyano-1,1,1-trifluorobut-3-en-2-yl) carbonate, substituted benzo[d]isothiazole-3-carboxylate 1,1-dioxide, substituted (9bS)-2-cyano-1-(trifluoromethyl)benzo[d]pyrrolo[1,2-b]isothiazole-9b(1H)-carboxylate 5,5-dioxide, (8α,9R)-(8′′α,9′′R)-9,9′′-[(2,5-Diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine Derivative[3+2] Annulation, Cyclization, Further Cyclizations
Amination, amides, α-diazoketones, chiral amides, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine Derivativealpha-Amination, Amination
Cyclopropanation, oxindoles, α-chloro-β-diketones, substituted tert-butyl 2′-oxospiro[cyclopropane-1,3′-indoline]-1′-carboxylate, N-[2,6-bis(1-methylethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-thiourea, Dihydroquinine DerivativeCyclopropanation, Spirocyclization
Cyclopropanation, oxindoles, bromonitroalkanes, substituted tert-butyl 2-nitro-2′-oxospiro[cyclopropane-1,3′-indoline]-1′-carboxylate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCyclopropanation, Spirocyclization
Fluorination, 3-functionalized 2-oxindoles, N-fluorbenzolsulfonimid, 3-functionalized 3-fluoro-2-oxindoles, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-tricyclo[3.3.1.13,7]dec-1-yl-urea, Quinine DerivativeFluorination, Fluorination
Aldol reaction, substituted 2-(benzylthio)-3,5-dihydro-4H-imidazol-4-one, pyridine 2-carbaldehyde N-oxides, substituted 2-((1S)-(2-(benzylthio)-5-oxo-4,5-dihydro-1H-imidazol-4-yl)(hydroxy)methyl)pyridine 1-oxide, N-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)-benzamide, Quinine DerivativeAldol, Aldol
Cyclopropanation, 2-bromomalonates, substituted 4-methylene-2,4-dihydro-3H-pyrazol-3-one, spirocyclopropyl pyrazolones, 1,4-bis[[(8α,9R)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]oxy]-9,10-Anthracenedione, Dihydroquinine DerivativeCyclopropanation, Spirocyclization
Hydrazination, 1,5-Dihydro-3-hydroxy-4-methyl-1-(1-naphthalenylmethyl)-2H-pyrrol-2-one, di-tert-butyl (E)-diazene-1,2-dicarboxylate, di-tert-butyl (R)-1-(3-methyl-1-(naphthalen-1-ylmethyl)-4,5-dioxopyrrolidin-3-yl)hydrazine-1,2-dicarboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-3-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)benzamide, N-[3,5-Bis(trifluoromethyl)phenyl]-3-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)benzamide, Quinine DerivativeFurther reactions, Hydrazination
Michael Addition, α-monosubstituted β-tetralones, nitroolefins, α-disubstituted β-tetralones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
