Michael Addition, substituted 3-(1H-pyrrol-1-yl)indolin-2-one-2-nitrobenzofuran, substituted 2-nitrobenzofuran, substituted (S)-3-((2S,3S)-2-nitro-2,3-dihydrobenzofuran-3-yl)-3-(1H-pyrrol-1-yl)indolin-2-one, (αS)-α-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-(8α,9S)-cinchonan-9-yl-benzenepropanamide, Cinchonidine DerivativeMichael, Michael Addition Spirocyclization, N-2,2,2-trifluoroethylisatin ketimines, aurones, bispiro[benzofuran-oxindole-pyrrolidine]s, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-N′-[4-(trifluoromethyl)phenyl]thiourea, Quinine DerivativeSpirocyclization Addition, 5H-oxazol-4-ones, γ-keto-α,β-unsaturated esters, highly functionalized γ-keto esters, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAddition Cascade reaction, 2-(nitrovinyl)phenols, cyclic dicarbonyl nucleophiles, polyfunctionalized chroman derivatives, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction Mannich reaction, 3-substituted benzofuran-2 (3H)-ones, N-Boc aminosulfones, 3,3-disubstitued benzofuran-2 (3H)-ones, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[(4-fluorophenyl)amino]carbonyl]amino]-6′-methoxy-Cinchonanium bromide, Quinine DerivativeMannich, Mannich Mannich reaction, cyclic sulfonylimines, pyruvates, substituted (S)-3-(2,2-dioxido-3,4-dihydrobenzo[e][1,2,3]oxathiazin-4-yl)-2-oxopropanoates, 2-nitrobenzoic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeMannich, Mannich Aza-Friedel-Crafts reaction, hydroxyindoles, pyrazolinone ketimines, substituted hydroxyindole derivatives, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAza-Friedel-Crafts, Friedel-Crafts Aza-Friedel-Crafts Alkylation, hydroxyquinolines, isatin-derived ketimines, 3-amino-2-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Friedel-Crafts, Friedel-Crafts Cascade reaction, diethyl 2,5-dihydroxy-1,4-dithiane-2,5-dicarboxylate, tert-butyl (Z)-3-nitro-2-phenylacrylate, 2-(tert-butyl) 4-ethyl (S)-3-nitro-2-phenyl-2,5-dihydrothiophene-2,4-dicarboxylate, 3-[(3,5-dimethylphenyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction [3+3]-Annulation, N-(benzo[b]thiophen-2-yl)-sulfonamide, 2-alkynyl cycloenone, dihydrobenzo[4,5]thieno[2,3-b]pyridine derivatives, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9R)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative[3+3]-Annulation, Further Cyclizations« Older EntriesNext Entries »
Michael Addition, substituted 3-(1H-pyrrol-1-yl)indolin-2-one-2-nitrobenzofuran, substituted 2-nitrobenzofuran, substituted (S)-3-((2S,3S)-2-nitro-2,3-dihydrobenzofuran-3-yl)-3-(1H-pyrrol-1-yl)indolin-2-one, (αS)-α-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-(8α,9S)-cinchonan-9-yl-benzenepropanamide, Cinchonidine DerivativeMichael, Michael Addition
Spirocyclization, N-2,2,2-trifluoroethylisatin ketimines, aurones, bispiro[benzofuran-oxindole-pyrrolidine]s, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-N′-[4-(trifluoromethyl)phenyl]thiourea, Quinine DerivativeSpirocyclization
Addition, 5H-oxazol-4-ones, γ-keto-α,β-unsaturated esters, highly functionalized γ-keto esters, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAddition
Cascade reaction, 2-(nitrovinyl)phenols, cyclic dicarbonyl nucleophiles, polyfunctionalized chroman derivatives, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction
Mannich reaction, 3-substituted benzofuran-2 (3H)-ones, N-Boc aminosulfones, 3,3-disubstitued benzofuran-2 (3H)-ones, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[(4-fluorophenyl)amino]carbonyl]amino]-6′-methoxy-Cinchonanium bromide, Quinine DerivativeMannich, Mannich
Mannich reaction, cyclic sulfonylimines, pyruvates, substituted (S)-3-(2,2-dioxido-3,4-dihydrobenzo[e][1,2,3]oxathiazin-4-yl)-2-oxopropanoates, 2-nitrobenzoic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeMannich, Mannich
Aza-Friedel-Crafts reaction, hydroxyindoles, pyrazolinone ketimines, substituted hydroxyindole derivatives, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAza-Friedel-Crafts, Friedel-Crafts
Aza-Friedel-Crafts Alkylation, hydroxyquinolines, isatin-derived ketimines, 3-amino-2-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Friedel-Crafts, Friedel-Crafts
Cascade reaction, diethyl 2,5-dihydroxy-1,4-dithiane-2,5-dicarboxylate, tert-butyl (Z)-3-nitro-2-phenylacrylate, 2-(tert-butyl) 4-ethyl (S)-3-nitro-2-phenyl-2,5-dihydrothiophene-2,4-dicarboxylate, 3-[(3,5-dimethylphenyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction
[3+3]-Annulation, N-(benzo[b]thiophen-2-yl)-sulfonamide, 2-alkynyl cycloenone, dihydrobenzo[4,5]thieno[2,3-b]pyridine derivatives, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9R)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative[3+3]-Annulation, Further Cyclizations
