Michael Addition, (E)-2-(2-nitrovinyl)furan, dimethyl malonate, dimethyl (R)-2-(1-(furan-2-yl)-2-nitroethyl)malonate, (9S)-(9′′S)-(9′′′′S)-9,9′′,9′′′′-[1,3,5-benzenetriyltris(methyleneoxy)]tris-cinchonan-6′-ol, Cupreidine DerivativeMichael, Michael Addition Spirocyclization, oxindoles, (E)-(2-nitrovinyl)benzene, spirooxindoles, (9S)-9-(9-anthracenylmethoxy)-cinchonan-6′-ol, Cupreidine DerivativeCascade reaction, Spirocyclization Aza-Michael Addition, 2-aminochalcones, 5-alkenyl-thiazolones, substituted (2R,10bR)-6-tosyl-1,2,3,5,6,10b-hexahydro-4H-2,4a-epithiobenzo[c][2,7]naphthyridin-4-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAza-Michael, Cyclization, Cyclization, Further Cyclizations, Mannich, Mannich, Michael Addition Aza-Michael Addition, substituted 3-hydroxy-3-(trifluoromethyl)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide, substituted 4-hydroxycyclohexa-2,5-dien-1-one, fluoroalkylated N,O-ketals, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Michael, Desymmetrization, Michael Addition Aza-Michael Addition, diacrylbenzols, N‐benzylhydroxylamine, 1,2‐benzoxazines, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeAza-Michael, Cascade reaction, Cyclization, Cyclization, Further Cyclizations, Michael Addition, Oxa-Michael Addition Phosphination, butyl 2-cyanopentanoate, chlorodiphenylphosphane, butyl (R)-2-cyano-2-(diphenylphosphaneyl)pentanoate, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)] bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeFurther reactions, Phosphination Cyclization, O‐allyl carbamates, N-bromosuccinimide, (4S,5S)-5-bromo-4-phenyl-3-tosyl-1,3-oxazinan-2-one, O-((S)-((1S,2R,4S,5R)-5-ethylquinuclidin-2-yl)(quinolin-4-yl)methyl) phenylcarbamothioate, Dihydrocinchonine DerivativeBromination, Cyclization, Cyclization, Further Cyclizations Desymmetrization, (1R,2S)-cyclohexane-1,2-diol, oxygen, (S)-2-hydroxycyclohexan-1-one, 4CzIPN, N-[(9R)-10,11-dihydrocinchonan-9-yl]-O-tert-butyl carbamate, Dihydrocinchonine DerivativeDesymmetrization Epimerization, substituted (1R,2S)-cyclohexane-1,2-diol, substituted (1S,2S)-cyclohexane-1,2-diol, 4CzIPN, N-[(9R)-10,11-dihydrocinchonan-9-yl]-O-tert-butyl carbamate, Dihydrocinchonine DerivativeDesymmetrization, Isomerization Epimerization, (1R,2S)-cycloheptane-1,2-diol, (1S,2S)-cycloheptane-1,2-diol, 4CzIPN, N-[(9R)-10,11-dihydrocinchonan-9-yl]-O-tert-butyl carbamate, Dihydrocinchonine DerivativeDesymmetrization, Isomerization« Older EntriesNext Entries »
Michael Addition, (E)-2-(2-nitrovinyl)furan, dimethyl malonate, dimethyl (R)-2-(1-(furan-2-yl)-2-nitroethyl)malonate, (9S)-(9′′S)-(9′′′′S)-9,9′′,9′′′′-[1,3,5-benzenetriyltris(methyleneoxy)]tris-cinchonan-6′-ol, Cupreidine DerivativeMichael, Michael Addition
Spirocyclization, oxindoles, (E)-(2-nitrovinyl)benzene, spirooxindoles, (9S)-9-(9-anthracenylmethoxy)-cinchonan-6′-ol, Cupreidine DerivativeCascade reaction, Spirocyclization
Aza-Michael Addition, 2-aminochalcones, 5-alkenyl-thiazolones, substituted (2R,10bR)-6-tosyl-1,2,3,5,6,10b-hexahydro-4H-2,4a-epithiobenzo[c][2,7]naphthyridin-4-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAza-Michael, Cyclization, Cyclization, Further Cyclizations, Mannich, Mannich, Michael Addition
Aza-Michael Addition, substituted 3-hydroxy-3-(trifluoromethyl)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide, substituted 4-hydroxycyclohexa-2,5-dien-1-one, fluoroalkylated N,O-ketals, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Michael, Desymmetrization, Michael Addition
Aza-Michael Addition, diacrylbenzols, N‐benzylhydroxylamine, 1,2‐benzoxazines, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeAza-Michael, Cascade reaction, Cyclization, Cyclization, Further Cyclizations, Michael Addition, Oxa-Michael Addition
Phosphination, butyl 2-cyanopentanoate, chlorodiphenylphosphane, butyl (R)-2-cyano-2-(diphenylphosphaneyl)pentanoate, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)] bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeFurther reactions, Phosphination
Cyclization, O‐allyl carbamates, N-bromosuccinimide, (4S,5S)-5-bromo-4-phenyl-3-tosyl-1,3-oxazinan-2-one, O-((S)-((1S,2R,4S,5R)-5-ethylquinuclidin-2-yl)(quinolin-4-yl)methyl) phenylcarbamothioate, Dihydrocinchonine DerivativeBromination, Cyclization, Cyclization, Further Cyclizations
Desymmetrization, (1R,2S)-cyclohexane-1,2-diol, oxygen, (S)-2-hydroxycyclohexan-1-one, 4CzIPN, N-[(9R)-10,11-dihydrocinchonan-9-yl]-O-tert-butyl carbamate, Dihydrocinchonine DerivativeDesymmetrization
Epimerization, substituted (1R,2S)-cyclohexane-1,2-diol, substituted (1S,2S)-cyclohexane-1,2-diol, 4CzIPN, N-[(9R)-10,11-dihydrocinchonan-9-yl]-O-tert-butyl carbamate, Dihydrocinchonine DerivativeDesymmetrization, Isomerization
Epimerization, (1R,2S)-cycloheptane-1,2-diol, (1S,2S)-cycloheptane-1,2-diol, 4CzIPN, N-[(9R)-10,11-dihydrocinchonan-9-yl]-O-tert-butyl carbamate, Dihydrocinchonine DerivativeDesymmetrization, Isomerization
