Atropisomer Synthesis, substituted 4-chloro-5-phenyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine, thiophenol, pyrrolopyrimidine scaffolds, 9-hydroxy-6′-methoxy-1-(phenylmethyl)- cinchonanium chloride, Quinine DerivativeAtropisomer synthesis Desymmetrization, substituted 4,6-dichloro-5-phenylpyrimidine, thiophenol, atropisomeric biaryls, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium chloride, Quinine DerivativeAtropisomer synthesis, Desymmetrization Aza-Michael Addition, ketones, tert-butyl hydrazinecarboxylate, pyrazolines, (8α,9R)-9-hydroxy-6′-methoxy-1-[(2-methoxyphenyl)methyl]-cinchonanium chloride, Quinine DerivativeAza-Michael, Michael Addition 4+2 Cycloaddition, 1-((2-(naphtho[2,1-b]furan-2-yl)phenyl)ethynyl)naphthalen-2-ol, (12aR,19aS)-5,5a-dihydro-12aH-benzo[f]indeno[1,2-c]naphtho[1′,2′:4,5]furo[3,2-b]chromene, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative[4+2]-Cycloaddition, Cycloaddition Addition, thioacetic acid, 3-(1-nitroethylidene)oxetane, (R)-S-(3-(1-nitroethyl)oxetan-3-yl) ethanethioate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAddition Michael Addition, barbituric acid derivative, 1-phenylprop-2-en-1-one, quaternary barbituric acid derivative, 3-[[3-[bis[3,5-bis(trifluoromethyl)phenyl]hydroxymethyl]-5-(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition Michael Addition, 2-(cyano(phenyl)methyl)pyridine-1-oxide, 4-hydroxy-4-methylpent-1-en-3-one, (R)-2-(1-cyano-5-hydroxy-5-methyl-4-oxo-1-phenylhexyl)pyridine-1-oxide, 4-[[(dimethylphenylsilyl)methyl]amino]-3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition Oxa-Michael, substituted cyclopropylbenzene, cyclopropane-fused chromanol structure, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Oxa-Michael Addition Epoxidation, (E)-chalcone, hydrogen peroxide, phenyl((2S,3R)-3-phenyloxiran-2-yl)methanone, (8α,9R)-(8′′α,9′′R)-1,1′′-[(2-fluoro-1,3-phenylene)bis(methylene)]bis[9-hydroxy-6′-methoxy-cinchonanium dibromide, Quinine DerivativeEpoxidation Epoxidation, α,β-unsaturated ketones, hydrogen peroxide, epoxy ketones, (8α,9R)-(8′′α,9′′R)-1,1′′-[(2-fluoro-1,3-phenylene)bis(methylene)]bis[9-hydroxy-6′-methoxy-cinchonanium dibromide, Quinine DerivativeEpoxidation« Older EntriesNext Entries »
Atropisomer Synthesis, substituted 4-chloro-5-phenyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine, thiophenol, pyrrolopyrimidine scaffolds, 9-hydroxy-6′-methoxy-1-(phenylmethyl)- cinchonanium chloride, Quinine DerivativeAtropisomer synthesis
Desymmetrization, substituted 4,6-dichloro-5-phenylpyrimidine, thiophenol, atropisomeric biaryls, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium chloride, Quinine DerivativeAtropisomer synthesis, Desymmetrization
Aza-Michael Addition, ketones, tert-butyl hydrazinecarboxylate, pyrazolines, (8α,9R)-9-hydroxy-6′-methoxy-1-[(2-methoxyphenyl)methyl]-cinchonanium chloride, Quinine DerivativeAza-Michael, Michael Addition
4+2 Cycloaddition, 1-((2-(naphtho[2,1-b]furan-2-yl)phenyl)ethynyl)naphthalen-2-ol, (12aR,19aS)-5,5a-dihydro-12aH-benzo[f]indeno[1,2-c]naphtho[1′,2′:4,5]furo[3,2-b]chromene, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative[4+2]-Cycloaddition, Cycloaddition
Addition, thioacetic acid, 3-(1-nitroethylidene)oxetane, (R)-S-(3-(1-nitroethyl)oxetan-3-yl) ethanethioate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAddition
Michael Addition, barbituric acid derivative, 1-phenylprop-2-en-1-one, quaternary barbituric acid derivative, 3-[[3-[bis[3,5-bis(trifluoromethyl)phenyl]hydroxymethyl]-5-(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
Michael Addition, 2-(cyano(phenyl)methyl)pyridine-1-oxide, 4-hydroxy-4-methylpent-1-en-3-one, (R)-2-(1-cyano-5-hydroxy-5-methyl-4-oxo-1-phenylhexyl)pyridine-1-oxide, 4-[[(dimethylphenylsilyl)methyl]amino]-3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
Oxa-Michael, substituted cyclopropylbenzene, cyclopropane-fused chromanol structure, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Oxa-Michael Addition
Epoxidation, (E)-chalcone, hydrogen peroxide, phenyl((2S,3R)-3-phenyloxiran-2-yl)methanone, (8α,9R)-(8′′α,9′′R)-1,1′′-[(2-fluoro-1,3-phenylene)bis(methylene)]bis[9-hydroxy-6′-methoxy-cinchonanium dibromide, Quinine DerivativeEpoxidation
Epoxidation, α,β-unsaturated ketones, hydrogen peroxide, epoxy ketones, (8α,9R)-(8′′α,9′′R)-1,1′′-[(2-fluoro-1,3-phenylene)bis(methylene)]bis[9-hydroxy-6′-methoxy-cinchonanium dibromide, Quinine DerivativeEpoxidation