Michael Addition, substituted ((nitromethyl)sulfonyl)benzene, α,β‐unsaturated ketones, α-nitro-δ-ketosulfones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition Strecker reaction, azomethine imines, trimethylsilyl cyanide, (S)-2-(3-oxopyrazolidin-1-yl)-2-Arylacetonitrile, N-[(1S,2R)-2-hydroxy-1,2-diphenylethyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]-thiourea, Quinine DerivativeStrecker Amination, 1,3-dicarbonyl compounds, dialkyl azodicarboxylates, 1-(1-carbonyl-2-oxocyclopentyl)hydrazine-1,2-dicarboxylate, 3,3′-[[(1S)-2,2′-dihydroxy[1,1′-binaphthalene]-3,3′-diyl]bis(methyleneimino)]bis[4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine Derivativealpha-Amination, Amination Spirocyclization, carbonyl compounds, spiroindolyloxindole, (8α,9R)-1-dodecyl-9-hydroxy-6′-methoxy-cinchonanium iodide, Quinine DerivativeSpirocyclization Mannich reaction, 6,8-dibromobenzo[e][1,2,3]oxathiazine 2,2-dioxide, β-Ketocarbonyls, ethyl (S)-4-(6,8-dibromo-2,2-dioxido-3,4-dihydrobenzo[e][1,2,3]oxathiazin-4-yl)-3-oxobutanoate, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeMannich, Mannich Michael Addition, aldehydes, nitroolefins, 3R-substituted 2,2-dimethyl-4-nitrobutanal, N-[(1R,2R)-2-Aminocyclohexyl]-N′-[(8α,9S)- 6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition Spirocyclization, unsaturated pyrazolones, 3-aryl-2-nitroprop-2-enols, Spirotetrahydropyranopyrazolones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Oxa-Michael Addition, Spirocyclization Friedel−Crafts Alkylation, 1H-indole, α,β‐unsaturated trifluoromethyl ketones, 4S-substituted 1,1,1-trifluoro-4-(1H-indol-3-yl)butan-2-one, 3-[[3,5-bis(1,1-dimethylethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeFriedel-Crafts, Friedel-Crafts alkylation Michael Addition, nitroalkenes, nitroalkanes, 2-substituted 1,3-dinitropentane, 3-[(1,1-dimethylethyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition Epoxidation Wharton-reaction sequence, 4,4-dimethylcyclohex-2-en-1-one, (R)-6,6-dimethylcyclohex-2-en-1-ol, (8α,9S)-6′-methoxy-Cinchonan-9-amine 2,2,2-trifluoroacetate (1:2), Quinine DerivativeEpoxidation, Further reactions, Wharton-reaction« Older EntriesNext Entries »
Michael Addition, substituted ((nitromethyl)sulfonyl)benzene, α,β‐unsaturated ketones, α-nitro-δ-ketosulfones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
Strecker reaction, azomethine imines, trimethylsilyl cyanide, (S)-2-(3-oxopyrazolidin-1-yl)-2-Arylacetonitrile, N-[(1S,2R)-2-hydroxy-1,2-diphenylethyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]-thiourea, Quinine DerivativeStrecker
Amination, 1,3-dicarbonyl compounds, dialkyl azodicarboxylates, 1-(1-carbonyl-2-oxocyclopentyl)hydrazine-1,2-dicarboxylate, 3,3′-[[(1S)-2,2′-dihydroxy[1,1′-binaphthalene]-3,3′-diyl]bis(methyleneimino)]bis[4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine Derivativealpha-Amination, Amination
Spirocyclization, carbonyl compounds, spiroindolyloxindole, (8α,9R)-1-dodecyl-9-hydroxy-6′-methoxy-cinchonanium iodide, Quinine DerivativeSpirocyclization
Mannich reaction, 6,8-dibromobenzo[e][1,2,3]oxathiazine 2,2-dioxide, β-Ketocarbonyls, ethyl (S)-4-(6,8-dibromo-2,2-dioxido-3,4-dihydrobenzo[e][1,2,3]oxathiazin-4-yl)-3-oxobutanoate, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeMannich, Mannich
Michael Addition, aldehydes, nitroolefins, 3R-substituted 2,2-dimethyl-4-nitrobutanal, N-[(1R,2R)-2-Aminocyclohexyl]-N′-[(8α,9S)- 6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
Spirocyclization, unsaturated pyrazolones, 3-aryl-2-nitroprop-2-enols, Spirotetrahydropyranopyrazolones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Oxa-Michael Addition, Spirocyclization
Friedel−Crafts Alkylation, 1H-indole, α,β‐unsaturated trifluoromethyl ketones, 4S-substituted 1,1,1-trifluoro-4-(1H-indol-3-yl)butan-2-one, 3-[[3,5-bis(1,1-dimethylethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeFriedel-Crafts, Friedel-Crafts alkylation
Michael Addition, nitroalkenes, nitroalkanes, 2-substituted 1,3-dinitropentane, 3-[(1,1-dimethylethyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
Epoxidation Wharton-reaction sequence, 4,4-dimethylcyclohex-2-en-1-one, (R)-6,6-dimethylcyclohex-2-en-1-ol, (8α,9S)-6′-methoxy-Cinchonan-9-amine 2,2,2-trifluoroacetate (1:2), Quinine DerivativeEpoxidation, Further reactions, Wharton-reaction
