Strecker Reaction, cyclic trifluoromethyl-ketoimines, trimethylsilyl cyanide, substituted 1-(4-methoxybenzyl)-2-oxo-1,2,3,4-tetrahydroquinazoline-4-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeStrecker Aza-Henry (Nitro-Mannich), ketimines, nitromethane, substituted 2-((4-methylphenyl)sulfonamido)-3-nitropropanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Cyclization, N-(heteroarenesulfonyl)imines, isocyanoacetates, imidazolines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations, Mannich, Mannich Cyclization, α‐imino esters, Isocyanoacetate, substituted 5-((4R,5R)-4-carboxylato-1-(2-hydroxyphenyl)-4,5-dihydro-1H-imidazol-5-yl)oxazole-4-carboxylate, 2-(diphenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine Derivative[3+2] Annulation, Cyclization, Further Cyclizations Mannich reaction, azlactones, isatin-derived ketimines, substituted 4-((S)-3-amino-2-oxoindolin-3-yl)oxazol-5(4H)-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich Mannich reaction, oxazolones, N-protected imines, N-((S)-((R)-4-methyl-5-oxo-2-phenyl-4,5-dihydrooxazol-4-yl)(phenyl)methyl)methanesulfonamide, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMannich, Mannich Mannich reaction, oxazolones, N-tosyl aldimines, substituted 4-methyl-N-((5-oxo-4,5-dihydrooxazol-4-yl)methyl)benzenesulfonamide, (8α,9R)-6′-Methoxy-9-[(trimethylsilyl)oxy]cinchonan, Quinine DerivativeMannich, Mannich Sulfa-Michael Addition, β,β-disubstituted nitroalkenes, para-methylthiophenol, ethyl (S)-3-nitro-2-phenyl-2-(p-tolylthio)propanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition Oxa-Michael Addition, (Z)-1,3-dimethyl-5-(3,3,3-trifluoro-1-nitroprop-1-en-2-yl)benzene, 4-methoxybenzaldehyde oxime, (S)-4-methoxybenzaldehyde O-(2-(3,5-dimethylphenyl)-1,1,1-trifluoro-3-nitropropan-2-yl) oxime, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Oxa-Michael Addition Aza-Michael Addition, β,β‐disubstituted nitroalkenes, benzotriazole, substituted 2-(1H-benzo[d][1,2,3]triazol-1-yl)-3-nitropropanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Michael, Michael Addition« Older EntriesNext Entries »
Strecker Reaction, cyclic trifluoromethyl-ketoimines, trimethylsilyl cyanide, substituted 1-(4-methoxybenzyl)-2-oxo-1,2,3,4-tetrahydroquinazoline-4-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeStrecker
Aza-Henry (Nitro-Mannich), ketimines, nitromethane, substituted 2-((4-methylphenyl)sulfonamido)-3-nitropropanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Cyclization, N-(heteroarenesulfonyl)imines, isocyanoacetates, imidazolines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations, Mannich, Mannich
Cyclization, α‐imino esters, Isocyanoacetate, substituted 5-((4R,5R)-4-carboxylato-1-(2-hydroxyphenyl)-4,5-dihydro-1H-imidazol-5-yl)oxazole-4-carboxylate, 2-(diphenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine Derivative[3+2] Annulation, Cyclization, Further Cyclizations
Mannich reaction, azlactones, isatin-derived ketimines, substituted 4-((S)-3-amino-2-oxoindolin-3-yl)oxazol-5(4H)-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich
Mannich reaction, oxazolones, N-protected imines, N-((S)-((R)-4-methyl-5-oxo-2-phenyl-4,5-dihydrooxazol-4-yl)(phenyl)methyl)methanesulfonamide, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMannich, Mannich
Mannich reaction, oxazolones, N-tosyl aldimines, substituted 4-methyl-N-((5-oxo-4,5-dihydrooxazol-4-yl)methyl)benzenesulfonamide, (8α,9R)-6′-Methoxy-9-[(trimethylsilyl)oxy]cinchonan, Quinine DerivativeMannich, Mannich
Sulfa-Michael Addition, β,β-disubstituted nitroalkenes, para-methylthiophenol, ethyl (S)-3-nitro-2-phenyl-2-(p-tolylthio)propanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition
Oxa-Michael Addition, (Z)-1,3-dimethyl-5-(3,3,3-trifluoro-1-nitroprop-1-en-2-yl)benzene, 4-methoxybenzaldehyde oxime, (S)-4-methoxybenzaldehyde O-(2-(3,5-dimethylphenyl)-1,1,1-trifluoro-3-nitropropan-2-yl) oxime, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Oxa-Michael Addition
Aza-Michael Addition, β,β‐disubstituted nitroalkenes, benzotriazole, substituted 2-(1H-benzo[d][1,2,3]triazol-1-yl)-3-nitropropanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Michael, Michael Addition
