Aza-Michael Addition, enones, tert-butyl (benzyloxy)carbamate, substituted tert-butyl (benzyloxy)(3-oxopropyl)carbamate, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAza-Michael, Michael Addition Epoxidation, enones, hydroperoxides, epoxy ketones, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeEpoxidation Nucleophilic Substitution, Cyclic Morita–Baylis–Hillman Alcohols, Indoles, substituted (E)-2-benzylidene-4-(1H-indol-3-yl)cyclopentan-1-one, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeFurther reactions, Nucleophilic Substitution Oxa-Michael, (E)-1-(4-bromo-3-methylphenyl)-3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-en-1-one, hydroxylamine, (S)-3-(4-bromo-3-methylphenyl)-5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole, (8α,9R)-1-(9-anthracenylmethyl)-9-hydroxy-6′- methoxy-cinchonanium bromide, Quinine DerivativeCyclization, Isoxazoline cyclization, Michael Addition, Oxa-Michael Addition Oxa-Michael, (E)-4,4,4-trifluoro-1,3-diphenylbut-2-en-1-one, hydroxylamine, (S)-3,5-diphenyl-5-(trifluoromethyl)-4,5-dihydroisoxazole, (8α,9R)-1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine DerivativeCyclization, Isoxazoline cyclization, Michael Addition, Oxa-Michael Addition Aldol reaction, cyclohexanone, 1-(dimethoxymethyl)-4-nitrobenzene, (S)-2-((R)-hydroxy(4-nitrophenyl)methyl)cyclohexan-1-one, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAldol, Aldol Spirocyclization, 4-unsaturated isoxazol-5-ones, α,α-dicyanoalkenes, substituted (R)-6-imino-1-oxo-2-oxa-3-azaspiro[4.5]deca-3,7-diene-7-carbonitrile, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Spirocyclization Spirocyclization, substituted ethyl (E)-3-((2-oxoindolin-3-yl)oxy)acrylate, substituted 4-methyleneisoxazol-5(4H)-one, isoxazolone-spirooxindoles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Spirocyclization Michael Addition, acetylacetone, (E)-(2-nitrovinyl)benzene, (S)-3-(2-nitro-1-phenylethyl)pentane-2,4-dione, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition Vinylogous Mannich reaction, 2‐ethylidene-1,3‐indandiones, isatin N‐Boc ketimines, tert-butyl (S)-(1-benzyl-3-(2-(1,3-dioxo-1,3-dihydro-2H-inden-2-ylidene)-2-phenylethyl)-5-methoxy-2-oxoindolin-3-yl)carbamate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMannich, Mannich« Older EntriesNext Entries »
Aza-Michael Addition, enones, tert-butyl (benzyloxy)carbamate, substituted tert-butyl (benzyloxy)(3-oxopropyl)carbamate, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAza-Michael, Michael Addition
Epoxidation, enones, hydroperoxides, epoxy ketones, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeEpoxidation
Nucleophilic Substitution, Cyclic Morita–Baylis–Hillman Alcohols, Indoles, substituted (E)-2-benzylidene-4-(1H-indol-3-yl)cyclopentan-1-one, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeFurther reactions, Nucleophilic Substitution
Oxa-Michael, (E)-1-(4-bromo-3-methylphenyl)-3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-en-1-one, hydroxylamine, (S)-3-(4-bromo-3-methylphenyl)-5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole, (8α,9R)-1-(9-anthracenylmethyl)-9-hydroxy-6′- methoxy-cinchonanium bromide, Quinine DerivativeCyclization, Isoxazoline cyclization, Michael Addition, Oxa-Michael Addition
Oxa-Michael, (E)-4,4,4-trifluoro-1,3-diphenylbut-2-en-1-one, hydroxylamine, (S)-3,5-diphenyl-5-(trifluoromethyl)-4,5-dihydroisoxazole, (8α,9R)-1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine DerivativeCyclization, Isoxazoline cyclization, Michael Addition, Oxa-Michael Addition
Aldol reaction, cyclohexanone, 1-(dimethoxymethyl)-4-nitrobenzene, (S)-2-((R)-hydroxy(4-nitrophenyl)methyl)cyclohexan-1-one, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAldol, Aldol
Spirocyclization, 4-unsaturated isoxazol-5-ones, α,α-dicyanoalkenes, substituted (R)-6-imino-1-oxo-2-oxa-3-azaspiro[4.5]deca-3,7-diene-7-carbonitrile, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Spirocyclization
Spirocyclization, substituted ethyl (E)-3-((2-oxoindolin-3-yl)oxy)acrylate, substituted 4-methyleneisoxazol-5(4H)-one, isoxazolone-spirooxindoles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Spirocyclization
Michael Addition, acetylacetone, (E)-(2-nitrovinyl)benzene, (S)-3-(2-nitro-1-phenylethyl)pentane-2,4-dione, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
Vinylogous Mannich reaction, 2‐ethylidene-1,3‐indandiones, isatin N‐Boc ketimines, tert-butyl (S)-(1-benzyl-3-(2-(1,3-dioxo-1,3-dihydro-2H-inden-2-ylidene)-2-phenylethyl)-5-methoxy-2-oxoindolin-3-yl)carbamate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMannich, Mannich