Mannich reaction, 2-pyridyl N-oxide acetates, N-Boc imines, α- and β-functionalized 2-substituted pyridines, Phenylmethyl N-[(1S)-1-[[[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]carbonyl]amino]-2,2-dimethylpropyl]carbamate, Quinine DerivativeMannich, Mannich Mannich reaction, imines, sulfonylacetonitriles, β-amino nitriles, 9H-Fluoren-9-ylmethyl N-[(1S)-1-[[[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]carbonyl]amino]-2,2-dimethylpropyl]carbamate, Quinine DerivativeMannich, Mannich Sulfa-Michael Addition, aromatic thiols, nitroalkenes, 2-nitro-1-arylethyl sulfides, (2S)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,3-dimethylbutanamide, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition [4+2]-Annulation, 3-nitroindoles, Nazarov reagents, hydrocarbazoles, (αS)-α-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzenepropanamide, Quinine Derivative[4+2] Annulation, Cyclization, Further Cyclizations Michael Addition, 3-substituted phthalides, nitroolefins, 3,3-disubstituted phthalide derivatives, (2S)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,3-dimethylbutanamide, Quinine DerivativeMichael, Michael Addition Cyclopropanation, oxindoles, bromonitroolefins, 3-spirocyclopropyl-2-oxindoles, (2S)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,3-dimethylbutanamide, Quinine DerivativeCyclopropanation, Spirocyclization [3+1]-Annulation, 3-chloro-1-methylindolin-2-one, benzoyl(3,4-dihydroisoquinolin-2-ium-2-yl)amide, (3S,3aR,8aS)-2-benzoyl-1′-methyl-1,3a,8,8a-tetrahydro-2H-spiro[indeno[2,1-c]pyrazole-3,3′-indolin]-2′-one, 6-Chloro-1-hydroxybenzotriazole, N-[(1R,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]-thiourea, Quinine Derivative[3+1]-Annulation, Cyclization, Further Cyclizations [4+2]-Cycloaddition, α,β-unsaturated aldehydes, nitroalkenes, acetic anhydride, subsituted cyclohexenes, N-[(1R,2S)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-N′-[(8α,9R)-6′-methoxycinchonan-9-yl]-thiourea, Quinine Derivative[4+2]-Cycloaddition, Cycloaddition Cyanoethoxycarbonylation, isatins, ethyl carbonocyanidate, substituted (R)-3-cyano-2-oxoindolin-3-yl ethyl carbonate, N-[(1S,2S)-2-[[[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]thioxomethyl]amino]-1,2-diphenylethyl]-3,5-bis(trifluoromethyl)-benzenesulfonamide linked to MCM-41, Quinine DerivativeCyanoethoxycarbonylation, Further reactions Cascade reaction, 2-(1-phenylpropylidene)-1H-indene-1,3(2H)-dione, (E)-1-bromo-2-(2-nitrovinyl)benzene, tetrahydrofluoren-9-ones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction« Older EntriesNext Entries »
Mannich reaction, 2-pyridyl N-oxide acetates, N-Boc imines, α- and β-functionalized 2-substituted pyridines, Phenylmethyl N-[(1S)-1-[[[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]carbonyl]amino]-2,2-dimethylpropyl]carbamate, Quinine DerivativeMannich, Mannich
Mannich reaction, imines, sulfonylacetonitriles, β-amino nitriles, 9H-Fluoren-9-ylmethyl N-[(1S)-1-[[[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]carbonyl]amino]-2,2-dimethylpropyl]carbamate, Quinine DerivativeMannich, Mannich
Sulfa-Michael Addition, aromatic thiols, nitroalkenes, 2-nitro-1-arylethyl sulfides, (2S)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,3-dimethylbutanamide, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition
[4+2]-Annulation, 3-nitroindoles, Nazarov reagents, hydrocarbazoles, (αS)-α-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzenepropanamide, Quinine Derivative[4+2] Annulation, Cyclization, Further Cyclizations
Michael Addition, 3-substituted phthalides, nitroolefins, 3,3-disubstituted phthalide derivatives, (2S)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,3-dimethylbutanamide, Quinine DerivativeMichael, Michael Addition
Cyclopropanation, oxindoles, bromonitroolefins, 3-spirocyclopropyl-2-oxindoles, (2S)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,3-dimethylbutanamide, Quinine DerivativeCyclopropanation, Spirocyclization
[3+1]-Annulation, 3-chloro-1-methylindolin-2-one, benzoyl(3,4-dihydroisoquinolin-2-ium-2-yl)amide, (3S,3aR,8aS)-2-benzoyl-1′-methyl-1,3a,8,8a-tetrahydro-2H-spiro[indeno[2,1-c]pyrazole-3,3′-indolin]-2′-one, 6-Chloro-1-hydroxybenzotriazole, N-[(1R,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]-thiourea, Quinine Derivative[3+1]-Annulation, Cyclization, Further Cyclizations
[4+2]-Cycloaddition, α,β-unsaturated aldehydes, nitroalkenes, acetic anhydride, subsituted cyclohexenes, N-[(1R,2S)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-N′-[(8α,9R)-6′-methoxycinchonan-9-yl]-thiourea, Quinine Derivative[4+2]-Cycloaddition, Cycloaddition
Cyanoethoxycarbonylation, isatins, ethyl carbonocyanidate, substituted (R)-3-cyano-2-oxoindolin-3-yl ethyl carbonate, N-[(1S,2S)-2-[[[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]thioxomethyl]amino]-1,2-diphenylethyl]-3,5-bis(trifluoromethyl)-benzenesulfonamide linked to MCM-41, Quinine DerivativeCyanoethoxycarbonylation, Further reactions
Cascade reaction, 2-(1-phenylpropylidene)-1H-indene-1,3(2H)-dione, (E)-1-bromo-2-(2-nitrovinyl)benzene, tetrahydrofluoren-9-ones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction
