Cascade reaction, aminooxylating compounds, nitroolefins, tetrahydro 1,2-oxazines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeCascade reaction Cascade reaction, N-Tosyl aminomethyl enones, trans-α-cyano-α,β-unsaturated ketones, highly substituted pyrrolidines, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeCascade reaction Aza-Michael Addition, bidentate aminomethyl enones, N-tosyl imines, 2,4-disubstituted imidazolidines, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeAza-Michael, Michael Addition Resolution, rac-BINOLs, (R)-BINOLs, N,N′-Di-tert-butylethylenediamine, Copper(I)-chloride, (8α,9R)-9-hydroxy-1-(phenylmethyl)-Cinchonanium chloride, Cinchonidine DerivativeRacemic resolution, Resolution Hydrophosphinylation, 2-methyl-3-(phenyl(tosyl)methyl)-1H-indole, bis(4-(trifluoromethyl)phenyl)phosphine oxide, (S)-((2-methyl-1H-indol-3-yl)(phenyl)methyl)bis(4-(trifluoromethyl)phenyl)phosphine oxide, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeFurther reactions, Hydrophosphinylation Oxa-Michael, oximes, β-CF3-β-disubstituted nitroalkenes, O-(1,1,1-trifluoro-3-nitro-2-substituted-propan-2-yl) oximes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Oxa-Michael Addition Vinylogous Michael addition, tert-butyl 2-oxo-3-(propan-2-ylidene)indoline-1-carboxylate, (E)-(3,3,3-trifluoro-1-nitroprop-1-en-2-yl)benzene, tert-butyl (R,Z)-2-oxo-3-(5,5,5-trifluoro-4-(nitromethyl)-4-phenylpentan-2-ylidene)indoline-1-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Vinylogous Michael Addition Sulfa-Michael Addition, β‐substituted‐β‐trifluoromethyl oxazolidinone enoates, mercaptans, substituted 3-(4,4,4-trifluoro-3-mercaptobutanoyl)oxazolidin-2-one, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition Sulfa-Michael Addition, β‐substituted‐β‐trifluoromethyl oxazolidinone enoates, mercaptans, substituted 3-(4,4,4-trifluoro-3-mercaptobutanoyl)oxazolidin-2-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition Spirocyclization, 3-isothiocyanato oxindoles, 3-nitroindoles, polycyclic spirooxindoles, (1β,4β,9R)-9-[N-[3,5-bis(trifluoromethyl)phenyl]carbamothioate]-6′-methoxy-Cinchonan-9-ol, Quinine DerivativeCascade reaction, Spirocyclization« Older EntriesNext Entries »
Cascade reaction, aminooxylating compounds, nitroolefins, tetrahydro 1,2-oxazines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeCascade reaction
Cascade reaction, N-Tosyl aminomethyl enones, trans-α-cyano-α,β-unsaturated ketones, highly substituted pyrrolidines, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeCascade reaction
Aza-Michael Addition, bidentate aminomethyl enones, N-tosyl imines, 2,4-disubstituted imidazolidines, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeAza-Michael, Michael Addition
Resolution, rac-BINOLs, (R)-BINOLs, N,N′-Di-tert-butylethylenediamine, Copper(I)-chloride, (8α,9R)-9-hydroxy-1-(phenylmethyl)-Cinchonanium chloride, Cinchonidine DerivativeRacemic resolution, Resolution
Hydrophosphinylation, 2-methyl-3-(phenyl(tosyl)methyl)-1H-indole, bis(4-(trifluoromethyl)phenyl)phosphine oxide, (S)-((2-methyl-1H-indol-3-yl)(phenyl)methyl)bis(4-(trifluoromethyl)phenyl)phosphine oxide, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeFurther reactions, Hydrophosphinylation
Oxa-Michael, oximes, β-CF3-β-disubstituted nitroalkenes, O-(1,1,1-trifluoro-3-nitro-2-substituted-propan-2-yl) oximes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Oxa-Michael Addition
Vinylogous Michael addition, tert-butyl 2-oxo-3-(propan-2-ylidene)indoline-1-carboxylate, (E)-(3,3,3-trifluoro-1-nitroprop-1-en-2-yl)benzene, tert-butyl (R,Z)-2-oxo-3-(5,5,5-trifluoro-4-(nitromethyl)-4-phenylpentan-2-ylidene)indoline-1-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Vinylogous Michael Addition
Sulfa-Michael Addition, β‐substituted‐β‐trifluoromethyl oxazolidinone enoates, mercaptans, substituted 3-(4,4,4-trifluoro-3-mercaptobutanoyl)oxazolidin-2-one, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition
Sulfa-Michael Addition, β‐substituted‐β‐trifluoromethyl oxazolidinone enoates, mercaptans, substituted 3-(4,4,4-trifluoro-3-mercaptobutanoyl)oxazolidin-2-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition
Spirocyclization, 3-isothiocyanato oxindoles, 3-nitroindoles, polycyclic spirooxindoles, (1β,4β,9R)-9-[N-[3,5-bis(trifluoromethyl)phenyl]carbamothioate]-6′-methoxy-Cinchonan-9-ol, Quinine DerivativeCascade reaction, Spirocyclization
