Conia-ene reaction, methyl 2-benzoylhept-6-ynoate, methyl (R)-1-benzoyl-2-methylenecyclopentane-1-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylurea, Cinchonidine DerivativeConia-ene reaction, Further reactions Spirocyclization, isatin, malononitrile, ethyl acetoacetate, ethyl (S)-2′-amino-3′-cyano-6′-methyl-2-oxospiro[indoline-3,4′-pyran]-5′-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeSpirocyclization Decarboxylative Protonation, 2-acetamido-2-benzyl-3-ethoxy-3-oxopropanoic acid, ethyl acetyl-D-phenylalaninate, N-(8α,9S)-Cinchonan-9-ylbenzenecarbothioamide, Cinchonidine DerivativeFurther reactions, Protonation Hydrosilylation, (S,E)-1-(3-(benzyloxy)phenyl)-N-(1-phenylethyl)ethan-1-imine, trichlorosilane, (S)-1-(3-(benzyloxy)phenyl)-N-((S)-1-phenylethyl)ethan-1-amine, (8α,9S)-1-(phenylmethyl)-9-[(2-pyridinylcarbonyl)amino]-Cinchonanium bromide, Cinchonidine DerivativeFurther reactions, Hydrogenation, Hydrogenation of imines, Hydrosilylation Isomerization of imines, trifluoromethyl imines, alkyl trifluoromethylated amines, (8α,9R)-2′-Chloro-10,11-dihydro-6′-methoxycinchonan-9-ol, Dihydroquinine DerivativeIsomerization Isomerization of imines, (E)-2,2,2-trifluoro-N-(4-nitrobenzyl)-1-phenylethan-1-imines, (R,E)-1-(4-nitrophenyl)-N-(2,2,2-trifluoro-1-phenylethyl)methanimines, (8α,9R)-2′-Chloro-10,11-dihydro-6′-methoxycinchonan-9-ol, Dihydroquinine DerivativeIsomerization Alkylation, gramine, tert-Butyl N-(diphenylmethylene)glycinate, N-(Diphenylmethylene)-L-tryptophan 1,1-dimethylethyl ester, (8α,9R)-1-(9-anthracenylmethyl)-9- (2-propenyloxy)-Cinchonanium bromide, Cinchonidine DerivativeAlkylation, Alkylation Hydrosilylation, (E)-N,1-diphenylpropan-1-imine, trichlorosilane, (R)-N-(1-phenylpropyl)aniline, 2-[[(8α,9S)-cinchonan-9-ylamino]carbonyl]-1-methyl-Pyridinium tetrafluoroborate, Cinchonidine DerivativeFurther reactions, Hydrogenation, Hydrogenation of imines, Hydrosilylation Alkylation, methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate, ethyl 2,2-difluoro-2-iodoacetate, methyl (R)-2-(2-ethoxy-1,1-difluoro-2-oxoethyl)-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, 1-[2-([1,1′-biphenyl]-2-ylamino)-2-oxoethyl]- 9-hydroxy-(8α,9R)-Cinchonanium bromide, Cinchonidine DerivativeAlkylation, Alkylation Alkylation, tert-butyl (1-benzyl-2-oxoindolin-3-yl)(2-chloroethyl)carbamate, tert-butyl (S)-1′-benzyl-2′-oxospiro[azetidine-2,3′-indoline]-1-carboxylate, (1S,2S,4S,5R)-2-((R)-hydroxy(quinolin-4-yl)methyl)-1-(4-(pentafluoro-l6-sulfaneyl)benzyl)-5-vinylquinuclidin-1-ium bromide, Cinchonidine DerivativeAlkylation, Alkylation, Spirocyclization« Older EntriesNext Entries »
Conia-ene reaction, methyl 2-benzoylhept-6-ynoate, methyl (R)-1-benzoyl-2-methylenecyclopentane-1-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylurea, Cinchonidine DerivativeConia-ene reaction, Further reactions
Spirocyclization, isatin, malononitrile, ethyl acetoacetate, ethyl (S)-2′-amino-3′-cyano-6′-methyl-2-oxospiro[indoline-3,4′-pyran]-5′-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeSpirocyclization
Decarboxylative Protonation, 2-acetamido-2-benzyl-3-ethoxy-3-oxopropanoic acid, ethyl acetyl-D-phenylalaninate, N-(8α,9S)-Cinchonan-9-ylbenzenecarbothioamide, Cinchonidine DerivativeFurther reactions, Protonation
Hydrosilylation, (S,E)-1-(3-(benzyloxy)phenyl)-N-(1-phenylethyl)ethan-1-imine, trichlorosilane, (S)-1-(3-(benzyloxy)phenyl)-N-((S)-1-phenylethyl)ethan-1-amine, (8α,9S)-1-(phenylmethyl)-9-[(2-pyridinylcarbonyl)amino]-Cinchonanium bromide, Cinchonidine DerivativeFurther reactions, Hydrogenation, Hydrogenation of imines, Hydrosilylation
Isomerization of imines, trifluoromethyl imines, alkyl trifluoromethylated amines, (8α,9R)-2′-Chloro-10,11-dihydro-6′-methoxycinchonan-9-ol, Dihydroquinine DerivativeIsomerization
Isomerization of imines, (E)-2,2,2-trifluoro-N-(4-nitrobenzyl)-1-phenylethan-1-imines, (R,E)-1-(4-nitrophenyl)-N-(2,2,2-trifluoro-1-phenylethyl)methanimines, (8α,9R)-2′-Chloro-10,11-dihydro-6′-methoxycinchonan-9-ol, Dihydroquinine DerivativeIsomerization
Alkylation, gramine, tert-Butyl N-(diphenylmethylene)glycinate, N-(Diphenylmethylene)-L-tryptophan 1,1-dimethylethyl ester, (8α,9R)-1-(9-anthracenylmethyl)-9- (2-propenyloxy)-Cinchonanium bromide, Cinchonidine DerivativeAlkylation, Alkylation
Hydrosilylation, (E)-N,1-diphenylpropan-1-imine, trichlorosilane, (R)-N-(1-phenylpropyl)aniline, 2-[[(8α,9S)-cinchonan-9-ylamino]carbonyl]-1-methyl-Pyridinium tetrafluoroborate, Cinchonidine DerivativeFurther reactions, Hydrogenation, Hydrogenation of imines, Hydrosilylation
Alkylation, methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate, ethyl 2,2-difluoro-2-iodoacetate, methyl (R)-2-(2-ethoxy-1,1-difluoro-2-oxoethyl)-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, 1-[2-([1,1′-biphenyl]-2-ylamino)-2-oxoethyl]- 9-hydroxy-(8α,9R)-Cinchonanium bromide, Cinchonidine DerivativeAlkylation, Alkylation
Alkylation, tert-butyl (1-benzyl-2-oxoindolin-3-yl)(2-chloroethyl)carbamate, tert-butyl (S)-1′-benzyl-2′-oxospiro[azetidine-2,3′-indoline]-1-carboxylate, (1S,2S,4S,5R)-2-((R)-hydroxy(quinolin-4-yl)methyl)-1-(4-(pentafluoro-l6-sulfaneyl)benzyl)-5-vinylquinuclidin-1-ium bromide, Cinchonidine DerivativeAlkylation, Alkylation, Spirocyclization