Michael Addition, nitroalkenes, curcumin derivatives, substituted 4-(2-nitroethyl)hepta-1,6-diene-3,5-dione, N-[(1S,2S)-2-[[[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]thioxomethyl]amino]-1,2-diphenylethyl]-4-nitro-benzenesulfonamide, Quinine DerivativeMichael, Michael Addition Friedel-Crafts Alkylation, imines, indoles, 3-subtituted indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine derivativeFriedel-Crafts, Friedel-Crafts alkylation Decarboxylative protonation, subtituted 2-(ethoxycarbonyl)-4-oxopentanoic acid, 2R-substituted ethyl 4-oxopentanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeFurther reactions, Protonation Cascade reaction, 3-cinnamoyloxazolidin-2-one, 2-mercaptobenzaldehyde, 3-((2R,3S,4R)-4-hydroxy-2-phenylthiochromane-3-carbonyl)oxazolidin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction Oxime addition, nitroalkenes, ethyl 2-(hydroxyimino)acetate, ethyl 2-((2-cyclohexyl-3-nitropropoxy)imino)acetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAddition Desymmetrization, (3aR,4S,7R,7aS)-3a,4,7,7a-tetrahydro-4,7-methanoisobenzofuran-1,3-dione, methanol, (1R,2S,3R,4S)-3-(methoxycarbonyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeDesymmetrization β-Lactam Cyclization, acyl chlorides, ethyl (E)-2-(tosylimino)acetate, β-lactams, Benzoylquinine, Quinine Derivative[2+2]-Cycloaddition, Cycloaddition Michael Addition, α-substituted isocyanoacetates, N-aryl maleimides, substituted 2-((R)-2,5-dioxopyrrolidin-3-yl)-2-isocyanoacetate, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Quinine Derivative Desymmetrization, 4-(4-fluorophenyl)dihydro-2H-pyran-2,6(3H)-dione, methanol, (R)-3-(4-fluorophenyl)-5-methoxy-5-oxopentanoic acid, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]- 3,5-bis(trifluoromethyl)benzenesulfonamide, Quinine DerivativeDesymmetrization Alkylation, 6,7-dichloro-5-methoxy-2-phenyl-2,3-dihydro-1H-inden-1-one, chloromethane, (S)-6,7-dichloro-5-methoxy-2-methyl-2-phenyl-2,3-dihydro-1H-inden-1-one, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium bromide, Quinine DerivativeAlkylation, Alkylation« Older EntriesNext Entries »
Michael Addition, nitroalkenes, curcumin derivatives, substituted 4-(2-nitroethyl)hepta-1,6-diene-3,5-dione, N-[(1S,2S)-2-[[[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]thioxomethyl]amino]-1,2-diphenylethyl]-4-nitro-benzenesulfonamide, Quinine DerivativeMichael, Michael Addition
Friedel-Crafts Alkylation, imines, indoles, 3-subtituted indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine derivativeFriedel-Crafts, Friedel-Crafts alkylation
Decarboxylative protonation, subtituted 2-(ethoxycarbonyl)-4-oxopentanoic acid, 2R-substituted ethyl 4-oxopentanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeFurther reactions, Protonation
Cascade reaction, 3-cinnamoyloxazolidin-2-one, 2-mercaptobenzaldehyde, 3-((2R,3S,4R)-4-hydroxy-2-phenylthiochromane-3-carbonyl)oxazolidin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction
Oxime addition, nitroalkenes, ethyl 2-(hydroxyimino)acetate, ethyl 2-((2-cyclohexyl-3-nitropropoxy)imino)acetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAddition
Desymmetrization, (3aR,4S,7R,7aS)-3a,4,7,7a-tetrahydro-4,7-methanoisobenzofuran-1,3-dione, methanol, (1R,2S,3R,4S)-3-(methoxycarbonyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeDesymmetrization
β-Lactam Cyclization, acyl chlorides, ethyl (E)-2-(tosylimino)acetate, β-lactams, Benzoylquinine, Quinine Derivative[2+2]-Cycloaddition, Cycloaddition
Michael Addition, α-substituted isocyanoacetates, N-aryl maleimides, substituted 2-((R)-2,5-dioxopyrrolidin-3-yl)-2-isocyanoacetate, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Quinine Derivative
Desymmetrization, 4-(4-fluorophenyl)dihydro-2H-pyran-2,6(3H)-dione, methanol, (R)-3-(4-fluorophenyl)-5-methoxy-5-oxopentanoic acid, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]- 3,5-bis(trifluoromethyl)benzenesulfonamide, Quinine DerivativeDesymmetrization
Alkylation, 6,7-dichloro-5-methoxy-2-phenyl-2,3-dihydro-1H-inden-1-one, chloromethane, (S)-6,7-dichloro-5-methoxy-2-methyl-2-phenyl-2,3-dihydro-1H-inden-1-one, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium bromide, Quinine DerivativeAlkylation, Alkylation
