Atropisomer Synthesis, 2-naphthalen-imidazoles, 1-(bromomethyl)-pentafluorobenzene, axially chiral imidazoles, (9S)-N-[(3,5-difluorophenyl)methyl]-6′,9-dihydroxy-cinchonanium bromide, Cupreidine DerivativeAtropisomer synthesis, Desymmetrization Spirocyclization, tert-butyl (1-benzyl-2-oxoindolin-3-yl)(2-chloroethyl)carbamate, tert-butyl (S)-1′-benzyl-2′-oxospiro[azetidine-2,3′-indoline]-1-carboxylate, (1S,2S,4S,5R)-2-((R)-hydroxy(quinolin-4-yl)methyl)-1-(4-(pentafluoro-l6-sulfaneyl)benzyl)-5-vinylquinuclidin-1-ium bromide, Cinchonidine DerivativeAlkylation, Spirocyclization Vinylogous Michael Addition, 5-methylfuran-2(3H)-one, tert-butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate, tert-butyl (R)-4-((R)-2-methyl-5-oxo-2,5-dihydrofuran-2-yl)-2-oxopyrrolidine-1-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeMichael Addition, Vinylogous Michael Addition Nazarov Cyclization, substituted (E)-hepta-4,6-diene-2,3-dione, substituted 5-hydroxy-4-methylenecyclopent-2-en-1-one, (3α,9S)-3,9-epoxy-10,11-dihydro-cinchonan-6′-ol, Dihydrocupreidine DerivativeCyclization, Further Cyclizations, Nazarov cyclization Decarboxylative Protonation, substituted 2-(ethoxycarbonyl)-4-oxopentanoic acid, substituted ethyl 4-oxopentanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeDecarboxylative Protonation, Protonation Atropisomer Synthesis, diethyl 2-(2-(benzyloxy)naphthalen-1-yl)-1-((tert-butoxycarbonyl)amino)-5-methyl-1H-pyrrole-3,4-dicarboxylate, methyl 2-(((tert-butoxycarbonyl)oxy)methyl)acrylate, 1,2-diaxial atropisomers, Dihydroquinidine BaseAtropisomer synthesis Cyclization, (phenylsulfonyl)acetonitrile, 4-fluorobenzaldehyde, 2-(benzylamino)ethan-1-ol, (R)-4-benzyl-3-(4-fluorophenyl)morpholin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeCascade reaction, Cyclization Cycloaddition, isochromane-1,3-dione, aldehydes, cis-Dihydroisocoumarins, 3-[[(8α,9S)-6′-Methoxycinchonan-9-yl]amino]-4-[(triphenylmethyl)amino]-3-cyclobutene-1,2-dione, Quinine DerivativeCycloaddition Cycloaddition, isochromane-1,3-dione, aldehydes, trans dihydroisocoumarins, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxy-2′-phenylcinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeCycloaddition Bromoaminocyclization, 4-nitro-N-(4-phenylpent-4-en-1-yl)benzenesulfonamide, N-Bromosuccinimide, (R)-2-(bromomethyl)-1-((4-nitrophenyl)sulfonyl)-2-phenylpyrrolidine, (8α,9R)-9-[N-(2,6-diethoxyphenyl)carbamothioate]-6′-methoxy-cinchonan-9-ol, Quinine DerivativeBromination, Bromoaminocyclization« Older EntriesNext Entries »
Atropisomer Synthesis, 2-naphthalen-imidazoles, 1-(bromomethyl)-pentafluorobenzene, axially chiral imidazoles, (9S)-N-[(3,5-difluorophenyl)methyl]-6′,9-dihydroxy-cinchonanium bromide, Cupreidine DerivativeAtropisomer synthesis, Desymmetrization
Spirocyclization, tert-butyl (1-benzyl-2-oxoindolin-3-yl)(2-chloroethyl)carbamate, tert-butyl (S)-1′-benzyl-2′-oxospiro[azetidine-2,3′-indoline]-1-carboxylate, (1S,2S,4S,5R)-2-((R)-hydroxy(quinolin-4-yl)methyl)-1-(4-(pentafluoro-l6-sulfaneyl)benzyl)-5-vinylquinuclidin-1-ium bromide, Cinchonidine DerivativeAlkylation, Spirocyclization
Vinylogous Michael Addition, 5-methylfuran-2(3H)-one, tert-butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate, tert-butyl (R)-4-((R)-2-methyl-5-oxo-2,5-dihydrofuran-2-yl)-2-oxopyrrolidine-1-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeMichael Addition, Vinylogous Michael Addition
Nazarov Cyclization, substituted (E)-hepta-4,6-diene-2,3-dione, substituted 5-hydroxy-4-methylenecyclopent-2-en-1-one, (3α,9S)-3,9-epoxy-10,11-dihydro-cinchonan-6′-ol, Dihydrocupreidine DerivativeCyclization, Further Cyclizations, Nazarov cyclization
Decarboxylative Protonation, substituted 2-(ethoxycarbonyl)-4-oxopentanoic acid, substituted ethyl 4-oxopentanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeDecarboxylative Protonation, Protonation
Atropisomer Synthesis, diethyl 2-(2-(benzyloxy)naphthalen-1-yl)-1-((tert-butoxycarbonyl)amino)-5-methyl-1H-pyrrole-3,4-dicarboxylate, methyl 2-(((tert-butoxycarbonyl)oxy)methyl)acrylate, 1,2-diaxial atropisomers, Dihydroquinidine BaseAtropisomer synthesis
Cyclization, (phenylsulfonyl)acetonitrile, 4-fluorobenzaldehyde, 2-(benzylamino)ethan-1-ol, (R)-4-benzyl-3-(4-fluorophenyl)morpholin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeCascade reaction, Cyclization
Cycloaddition, isochromane-1,3-dione, aldehydes, cis-Dihydroisocoumarins, 3-[[(8α,9S)-6′-Methoxycinchonan-9-yl]amino]-4-[(triphenylmethyl)amino]-3-cyclobutene-1,2-dione, Quinine DerivativeCycloaddition
Cycloaddition, isochromane-1,3-dione, aldehydes, trans dihydroisocoumarins, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxy-2′-phenylcinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeCycloaddition
Bromoaminocyclization, 4-nitro-N-(4-phenylpent-4-en-1-yl)benzenesulfonamide, N-Bromosuccinimide, (R)-2-(bromomethyl)-1-((4-nitrophenyl)sulfonyl)-2-phenylpyrrolidine, (8α,9R)-9-[N-(2,6-diethoxyphenyl)carbamothioate]-6′-methoxy-cinchonan-9-ol, Quinine DerivativeBromination, Bromoaminocyclization
