Michael Addition, dimethyl malonate, nitroolefins, substituted dimethyl 2-(2-nitroethyl)malonate, Cupreine BaseMichael, Michael Addition Michael Addition, alpha,beta-unsaturated esters, gamma-substituted butenolides, gamma,gamma-disubstituted butenolides, Cupreine BaseMichael, Michael Addition Henry reaction (Nitroaldol), 1-naphthaldehyde, nitromethane, (R)-1-(naphthalen-1-yl)-2-nitroethan-1-ol, 1-(4-((R)-(benzyloxy)((1S,2S,4S,5R)-5-vinylquinuclidin- 2-yl)methyl)quinolin-6-yl)-3-(3,5-bis(trifluoromethyl)phenyl) thiourea, 6´-Aminocinchonidine DerivativeAldol, Henry, Henry, Nitroaldol Aza Henry (Nitro-Mannich), 6-chloro-1-(4-methoxybenzyl)-4-(trifluoromethyl)quinazolin-2(1H)-one, nitromethane, (R)-6-chloro-1-(4-methoxybenzyl)-4-(nitromethyl)-4-(trifluoromethyl)-3,4-dihydroquinazolin-2(1H)-one, 1-(4-((R)-(benzyloxy)((1S,2S,4S,5R)-5-vinylquinuclidin- 2-yl)methyl)quinolin-6-yl)-3-(3,5-bis(trifluoromethyl)phenyl) thiourea, 6´-Aminocinchonidine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Aza Henry (Nitro-Mannich), substituted 1-(4-methoxybenzyl)-4-(trifluoromethyl)quinazolin-2(1H)-one, nitroalkane, substituted (R)-1-(4-methoxybenzyl)-4-((S)-1-nitroethyl)-4-(trifluoromethyl)-3,4-dihydroquinazolin-2(1H)-one, 1-(4-((R)-(benzyloxy)((1S,2S,4S,5R)-5-vinylquinuclidin- 2-yl)methyl)quinolin-6-yl)-3-(3,5-bis(trifluoromethyl)phenyl) thiourea, 6´-Aminocinchonidine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Aza Henry (Nitro-Mannich), cyclic iminoesters, nitroalkane, tetrasubstituted cyclic amines, N-(8α,9S)-Cinchonan-9-yl-8-quinolinesulfonamide, Cinchonidine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Michael Addition/Aldol cascade/Cyclization, alpha,beta unsaturated 7-azaindoline amide, 2-mercaptobenzaldehyde, thiochromans, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [(8α,9S)-cinchonan-9-ylamino]- 3-Cyclobutene-1,2-dione, Cinchonidine DerivativeAldol, Aldol, Cyclization, Further Cyclizations, Michael Addition, Sulfa-Michael Domino Michael – Alkylation, methyleneindolinones, gamma-halogenated-beta-ketoesters, spiro-cyclopentanoneoxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeCascade reaction, Cyclization Michael Addition, 2-oxindoles, vinyl selenone, 3-(2-(phenylselenonyl)ethyl)indolin-2-ones, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeMichael, Michael Addition Spirocyclization/Diels Alder/Michael Addition, 2-ethylidene-indanedione, alpha,beta unsaturated ketone, indanedione-fused 2,6-disubstituted trans-spirocyclohexanone, indanedione-fused 2,6-disubstituted cis-spirocyclohexanone, (8α,9S)-Cinchonan-9-amine, Cinchonidine DerivativeCycloaddition, Diels-Alder reaction, Michael, Michael Addition« Older EntriesNext Entries »
Michael Addition, dimethyl malonate, nitroolefins, substituted dimethyl 2-(2-nitroethyl)malonate, Cupreine BaseMichael, Michael Addition
Michael Addition, alpha,beta-unsaturated esters, gamma-substituted butenolides, gamma,gamma-disubstituted butenolides, Cupreine BaseMichael, Michael Addition
Henry reaction (Nitroaldol), 1-naphthaldehyde, nitromethane, (R)-1-(naphthalen-1-yl)-2-nitroethan-1-ol, 1-(4-((R)-(benzyloxy)((1S,2S,4S,5R)-5-vinylquinuclidin- 2-yl)methyl)quinolin-6-yl)-3-(3,5-bis(trifluoromethyl)phenyl) thiourea, 6´-Aminocinchonidine DerivativeAldol, Henry, Henry, Nitroaldol
Aza Henry (Nitro-Mannich), 6-chloro-1-(4-methoxybenzyl)-4-(trifluoromethyl)quinazolin-2(1H)-one, nitromethane, (R)-6-chloro-1-(4-methoxybenzyl)-4-(nitromethyl)-4-(trifluoromethyl)-3,4-dihydroquinazolin-2(1H)-one, 1-(4-((R)-(benzyloxy)((1S,2S,4S,5R)-5-vinylquinuclidin- 2-yl)methyl)quinolin-6-yl)-3-(3,5-bis(trifluoromethyl)phenyl) thiourea, 6´-Aminocinchonidine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Aza Henry (Nitro-Mannich), substituted 1-(4-methoxybenzyl)-4-(trifluoromethyl)quinazolin-2(1H)-one, nitroalkane, substituted (R)-1-(4-methoxybenzyl)-4-((S)-1-nitroethyl)-4-(trifluoromethyl)-3,4-dihydroquinazolin-2(1H)-one, 1-(4-((R)-(benzyloxy)((1S,2S,4S,5R)-5-vinylquinuclidin- 2-yl)methyl)quinolin-6-yl)-3-(3,5-bis(trifluoromethyl)phenyl) thiourea, 6´-Aminocinchonidine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Aza Henry (Nitro-Mannich), cyclic iminoesters, nitroalkane, tetrasubstituted cyclic amines, N-(8α,9S)-Cinchonan-9-yl-8-quinolinesulfonamide, Cinchonidine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Michael Addition/Aldol cascade/Cyclization, alpha,beta unsaturated 7-azaindoline amide, 2-mercaptobenzaldehyde, thiochromans, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [(8α,9S)-cinchonan-9-ylamino]- 3-Cyclobutene-1,2-dione, Cinchonidine DerivativeAldol, Aldol, Cyclization, Further Cyclizations, Michael Addition, Sulfa-Michael
Domino Michael – Alkylation, methyleneindolinones, gamma-halogenated-beta-ketoesters, spiro-cyclopentanoneoxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeCascade reaction, Cyclization
Michael Addition, 2-oxindoles, vinyl selenone, 3-(2-(phenylselenonyl)ethyl)indolin-2-ones, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeMichael, Michael Addition
Spirocyclization/Diels Alder/Michael Addition, 2-ethylidene-indanedione, alpha,beta unsaturated ketone, indanedione-fused 2,6-disubstituted trans-spirocyclohexanone, indanedione-fused 2,6-disubstituted cis-spirocyclohexanone, (8α,9S)-Cinchonan-9-amine, Cinchonidine DerivativeCycloaddition, Diels-Alder reaction, Michael, Michael Addition
