Spirocyclization domino Aza-Michael/Michael Addition, 4-alkylidene-2,4-dihydro-3H-pyrazol-3-one, alpha,beta unsaturated ketones, Spiropyrazolone Tetrahydroquinolines, 3-[[(9R)-6′-Methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeCascade reaction, Spirocyclization Aza-Michael Addition, (E)-4-methyl-N-(2-(3-oxo-3-phenylprop-1-en-1-yl)phenyl)benzenesulfonamide, (Z)-3-benzylidenebenzofuran-2(3H)-one, (2’R,3R,4’R)-4′-(2-oxo-2-phenylethyl)-2′-phenyl-1′-tosyl-1′,4′-dihydro-2H,2’H-spiro[benzofuran-3,3′-quinolin]-2-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeAza-Michael, Michael Addition Sulfa-Michael Addition, thiols, alpha,beta-unsaturated diazoketones, beta-(alkylthio) diazoketones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition Sulfa-Michael Addition, substituted ethyl (E)-3-(2-mercaptophenyl)acrylates, nitroolefins, substituted thiochromanes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition Domino Sulfa-Michael/Aldol reaction, 1,4-dithiane-2,5-diol, chalkones, trisubstituted tetrahydrothiophenes, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Cyclization Michael Addition, (E)-4-methyl-1-nitropent-1-ene, dimethyl malonate, dimethyl (S)-2-(4-methyl-1-nitropentan-2-yl)malonate, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeMichael, Michael Addition Sulfa-Michael Addition, methyl 2-mercaptoacetate, (E)-3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one, methyl (R)-2-((1-(4-methoxyphenyl)-3-oxo-3-phenylpropyl)thio)acetate, 3-[[(8α,9S)-6′-Methoxycinchonan-9-yl]amino]-4- (tricyclo[3.3.1.13,7]dec-2-ylamino)-3- cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition Michael Addition, (E)-chalcone, nitromethane, (R)-4-nitro-1,3-diphenylbutan-1-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition Sulfa-Michael Addition, alpha,beta-unsaturated N-acylated succinimides, thiols, beta-sulfated thioester derivatives, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition Michael Addition, alpha,beta unsaturated ketones, nitromethane, beta-(nitromethyl)-ketones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition« Older EntriesNext Entries »
Spirocyclization domino Aza-Michael/Michael Addition, 4-alkylidene-2,4-dihydro-3H-pyrazol-3-one, alpha,beta unsaturated ketones, Spiropyrazolone Tetrahydroquinolines, 3-[[(9R)-6′-Methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeCascade reaction, Spirocyclization
Aza-Michael Addition, (E)-4-methyl-N-(2-(3-oxo-3-phenylprop-1-en-1-yl)phenyl)benzenesulfonamide, (Z)-3-benzylidenebenzofuran-2(3H)-one, (2’R,3R,4’R)-4′-(2-oxo-2-phenylethyl)-2′-phenyl-1′-tosyl-1′,4′-dihydro-2H,2’H-spiro[benzofuran-3,3′-quinolin]-2-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeAza-Michael, Michael Addition
Sulfa-Michael Addition, thiols, alpha,beta-unsaturated diazoketones, beta-(alkylthio) diazoketones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition
Sulfa-Michael Addition, substituted ethyl (E)-3-(2-mercaptophenyl)acrylates, nitroolefins, substituted thiochromanes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition
Domino Sulfa-Michael/Aldol reaction, 1,4-dithiane-2,5-diol, chalkones, trisubstituted tetrahydrothiophenes, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Cyclization
Michael Addition, (E)-4-methyl-1-nitropent-1-ene, dimethyl malonate, dimethyl (S)-2-(4-methyl-1-nitropentan-2-yl)malonate, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeMichael, Michael Addition
Sulfa-Michael Addition, methyl 2-mercaptoacetate, (E)-3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one, methyl (R)-2-((1-(4-methoxyphenyl)-3-oxo-3-phenylpropyl)thio)acetate, 3-[[(8α,9S)-6′-Methoxycinchonan-9-yl]amino]-4- (tricyclo[3.3.1.13,7]dec-2-ylamino)-3- cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition
Michael Addition, (E)-chalcone, nitromethane, (R)-4-nitro-1,3-diphenylbutan-1-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
Sulfa-Michael Addition, alpha,beta-unsaturated N-acylated succinimides, thiols, beta-sulfated thioester derivatives, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition
Michael Addition, alpha,beta unsaturated ketones, nitromethane, beta-(nitromethyl)-ketones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
