Alkylation, 3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, tert-butyl 4-((methylsulfonyl)oxy)piperidine-1-carboxylate, (R)-3,10-dibromo-8-chloro-11-(piperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, Quinine BaseAlkylation, Alkylation Desymmetrization, (3aR,7aS)-3a,7a-dimethyl-3a,7a-dihydroisobenzofuran-1,3-dione, methanol, (1R,6S)-6-(methoxycarbonyl)-1,6-dimethylcyclohexa-2,4-diene-1-carboxylic acid, Quinine BaseDesymmetrization Acetylide Addition, 1-substituted-6-chloro-4-cyclopropylquinazolin-2(1H)-one, 2-ethynylpyridine, (S)-1-substituted-6-chloro-4-cyclopropyl-4-(pyridin-2-ylethynyl)-3,4-dihydroquinazolin-2(1H)-one, Quinine BaseAcetylide Addition, Addition Aza-Henry (Nitro-Mannich), (E)-N’-ethylidene-4-nitrobenzohydrazide, nitromethane, 4-nitro-N’-(1-nitropropan-2-yl)benzohydrazide, Quinine BaseAza-Henry, Henry, Mannich, Nitro-Mannich Amination, 4-substituted-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, disubstituted-(E)-diazene-1,2-dicarboxylate, (1-(4-substituted-3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)hydrazine-1,2-diyl)bis((substituted)oxy)methanone), Quinine BaseAmination Phospha Michael Addition, diphenyl phosphonate, (E)-2-(2-nitrovinyl)thiophene, diphenyl (R)-(2-nitro-1-(thiophen-2-yl)ethyl)phosphonate, Quinine BaseMichael Addition, Phospha-Michael Addition Phospha Mannich reaction, diethyl phosphonate, tert-butyl (E)-benzylidenecarbamate, tert-butyl (S)-(diethoxyphosphoryl)(phenyl)methylcarbamate, Quinine BaseMannich, Phospha-Mannich Michael Addition, nitroethane, (E)-(2-nitrovinyl)benzene, ((2S,3S)-1,3-dinitrobutan-2-yl)benzene, 3,4-Bis[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition Epoxidation, (E)-1,3-diphenylprop-2-en-1-ol, sodium hypochlorite, phenyl((2S,3R)-3-phenyloxiran-2-yl)methanone, 1-(9-anthracenylmethyl)-10,11-dihydro-9-(phenylmethoxy)-(8α,9R)-Cinchonanium bromide, Dihydrocinchonidine DerivativeEpoxidation Hydrogenation, diethyl 2-oxopentanedioate, hydrogen, p-toluenesulfonic acid, ethyl (R)-5-oxotetrahydrofuran-2-carboxylate, platinum/aluminiumoxide, (8α,9R)-10,11-Dihydro-9-methoxycinchonan, Dihydrocinchonidine DerivativeHydrogenation, Hydrogenation of alpha-ketoesters« Older EntriesNext Entries »
Alkylation, 3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, tert-butyl 4-((methylsulfonyl)oxy)piperidine-1-carboxylate, (R)-3,10-dibromo-8-chloro-11-(piperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, Quinine BaseAlkylation, Alkylation
Desymmetrization, (3aR,7aS)-3a,7a-dimethyl-3a,7a-dihydroisobenzofuran-1,3-dione, methanol, (1R,6S)-6-(methoxycarbonyl)-1,6-dimethylcyclohexa-2,4-diene-1-carboxylic acid, Quinine BaseDesymmetrization
Acetylide Addition, 1-substituted-6-chloro-4-cyclopropylquinazolin-2(1H)-one, 2-ethynylpyridine, (S)-1-substituted-6-chloro-4-cyclopropyl-4-(pyridin-2-ylethynyl)-3,4-dihydroquinazolin-2(1H)-one, Quinine BaseAcetylide Addition, Addition
Aza-Henry (Nitro-Mannich), (E)-N’-ethylidene-4-nitrobenzohydrazide, nitromethane, 4-nitro-N’-(1-nitropropan-2-yl)benzohydrazide, Quinine BaseAza-Henry, Henry, Mannich, Nitro-Mannich
Amination, 4-substituted-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, disubstituted-(E)-diazene-1,2-dicarboxylate, (1-(4-substituted-3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)hydrazine-1,2-diyl)bis((substituted)oxy)methanone), Quinine BaseAmination
Phospha Michael Addition, diphenyl phosphonate, (E)-2-(2-nitrovinyl)thiophene, diphenyl (R)-(2-nitro-1-(thiophen-2-yl)ethyl)phosphonate, Quinine BaseMichael Addition, Phospha-Michael Addition
Phospha Mannich reaction, diethyl phosphonate, tert-butyl (E)-benzylidenecarbamate, tert-butyl (S)-(diethoxyphosphoryl)(phenyl)methylcarbamate, Quinine BaseMannich, Phospha-Mannich
Michael Addition, nitroethane, (E)-(2-nitrovinyl)benzene, ((2S,3S)-1,3-dinitrobutan-2-yl)benzene, 3,4-Bis[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
Epoxidation, (E)-1,3-diphenylprop-2-en-1-ol, sodium hypochlorite, phenyl((2S,3R)-3-phenyloxiran-2-yl)methanone, 1-(9-anthracenylmethyl)-10,11-dihydro-9-(phenylmethoxy)-(8α,9R)-Cinchonanium bromide, Dihydrocinchonidine DerivativeEpoxidation
Hydrogenation, diethyl 2-oxopentanedioate, hydrogen, p-toluenesulfonic acid, ethyl (R)-5-oxotetrahydrofuran-2-carboxylate, platinum/aluminiumoxide, (8α,9R)-10,11-Dihydro-9-methoxycinchonan, Dihydrocinchonidine DerivativeHydrogenation, Hydrogenation of alpha-ketoesters