Spirocyclization, (Z)-5-(2-methylbenzylidene)-2-phenylthiazol-4(5H)-one, 3-chloroindolin-2-one, (2’S,3R,3’S)-2”-phenyl-3′-(o-tolyl)-4”H-dispiro[indoline-3,1′-cyclopropane-2′,5”-thiazole]-2,4”-dione, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeAlkylation, Alkylation, Cascade reaction, Cyclopropanation, Spirocyclization Aza-Henry, (Nitro-Mannich), substituted-tert-butyl(tosylmethyl)carbamate, tert-butyldimethyl(4-nitrobutoxy)silane, tert-butyl ((1R,2S)-5-((tert-butyldimethylsilyl)oxy)-1-substituted-2-nitropentyl)carbamate, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium chloride, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Aza-Henry, (Nitro-Mannich), tert-butyl (E)-(4-chlorobenzylidene)carbamate, nitromethane, tert-butyl (S)-(1-(4-chlorophenyl)-2-nitroethyl)carbamate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Aza-Henry, (Nitro-Mannich), tert-butyl ((4-chlorophenyl)(tosyl)methyl)carbamate, nitroethane, tert-butyl ((1R,2S)-1-(4-chlorophenyl)-2-nitropropyl)carbamate, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium chloride, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Aza-Henry, (Nitro-Mannich), tert-butyl (3-phenyl-1-tosylpropyl)carbamate, nitromethane, tert-butyl (R)-(1-nitro-4-phenylbutan-2-yl)carbamate, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium chloride, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Vinylogous Michael Addition, tert-butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate, α,β-unsaturated ketones, tert-butyl 2-((S)-1,3-disubstituted-3-oxopropyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Vinylogous Michael Addition Henry reaction, aldehydes, nitroalkanes, beta-nitroalcohols, 2,4-bis(1,1-dimethylethyl)-6-[(E)-[[(8α,9S)-6′-methoxycinchonan-9-yl]imino]methyl]-phenol, Quinine DerivativeAldol, Henry, Henry, Nitroaldol Aza-Henry, (Nitro-Mannich), substituted-tert-butyl (Z)-(1-benzyl-2-oxoindolin-3-ylidene)carbamate, nitromethane, substituted-tert-butyl (R)-(1-benzyl-3-(nitromethyl)-2-oxoindolin-3-yl)carbamate, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[[(1S)-2-hydroxy-1-phenylethyl]amino]carbonyl]amino]-6′-methoxy-Cinchonanium bromide, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Aza-Henry, (Nitro-Mannich), substituted 2-(tosylimino)acetate, nitromethane, substituted (R)-2-((4-methylphenyl)sulfonamido)-3-nitropropanoate, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-6′-methoxy-Cinchonanium bromide, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Epoxidation, (E)-3-phenyl-2-(phenylsulfonyl)acrylonitrile, tert-Butylhydroperoxid, 3-phenyl-2-(phenylsulfonyl)oxirane-2-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeEpoxidation« Older EntriesNext Entries »
Spirocyclization, (Z)-5-(2-methylbenzylidene)-2-phenylthiazol-4(5H)-one, 3-chloroindolin-2-one, (2’S,3R,3’S)-2”-phenyl-3′-(o-tolyl)-4”H-dispiro[indoline-3,1′-cyclopropane-2′,5”-thiazole]-2,4”-dione, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeAlkylation, Alkylation, Cascade reaction, Cyclopropanation, Spirocyclization
Aza-Henry, (Nitro-Mannich), substituted-tert-butyl(tosylmethyl)carbamate, tert-butyldimethyl(4-nitrobutoxy)silane, tert-butyl ((1R,2S)-5-((tert-butyldimethylsilyl)oxy)-1-substituted-2-nitropentyl)carbamate, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium chloride, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Aza-Henry, (Nitro-Mannich), tert-butyl (E)-(4-chlorobenzylidene)carbamate, nitromethane, tert-butyl (S)-(1-(4-chlorophenyl)-2-nitroethyl)carbamate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Aza-Henry, (Nitro-Mannich), tert-butyl ((4-chlorophenyl)(tosyl)methyl)carbamate, nitroethane, tert-butyl ((1R,2S)-1-(4-chlorophenyl)-2-nitropropyl)carbamate, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium chloride, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Aza-Henry, (Nitro-Mannich), tert-butyl (3-phenyl-1-tosylpropyl)carbamate, nitromethane, tert-butyl (R)-(1-nitro-4-phenylbutan-2-yl)carbamate, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium chloride, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Vinylogous Michael Addition, tert-butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate, α,β-unsaturated ketones, tert-butyl 2-((S)-1,3-disubstituted-3-oxopropyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Vinylogous Michael Addition
Henry reaction, aldehydes, nitroalkanes, beta-nitroalcohols, 2,4-bis(1,1-dimethylethyl)-6-[(E)-[[(8α,9S)-6′-methoxycinchonan-9-yl]imino]methyl]-phenol, Quinine DerivativeAldol, Henry, Henry, Nitroaldol
Aza-Henry, (Nitro-Mannich), substituted-tert-butyl (Z)-(1-benzyl-2-oxoindolin-3-ylidene)carbamate, nitromethane, substituted-tert-butyl (R)-(1-benzyl-3-(nitromethyl)-2-oxoindolin-3-yl)carbamate, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[[(1S)-2-hydroxy-1-phenylethyl]amino]carbonyl]amino]-6′-methoxy-Cinchonanium bromide, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Aza-Henry, (Nitro-Mannich), substituted 2-(tosylimino)acetate, nitromethane, substituted (R)-2-((4-methylphenyl)sulfonamido)-3-nitropropanoate, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-6′-methoxy-Cinchonanium bromide, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Epoxidation, (E)-3-phenyl-2-(phenylsulfonyl)acrylonitrile, tert-Butylhydroperoxid, 3-phenyl-2-(phenylsulfonyl)oxirane-2-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeEpoxidation
