Cyanation of unsaturated ketones, tert-butyl (E)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-2-methylbenzoate, 2-hydroxy-2-methylpropanenitrile, cyanopotassium, tert-butyl (R)-4-(3-cyano-3-(3,5-dichlorophenyl)-4,4,4-trifluorobutanoyl)-2-methylbenzoate, 9-hydroxy-6′-methoxy-1-[(2,3,4,5,6-pentafluorophenyl)methyl]-cinchonanium bromide, Quinine DerivativeCyanation Michael addition, 2,3-substituted 3-oxopropanoate, 1-substituted ethene, 2,2,3-tritrisubstituted-(R)-3-oxopropanoate, 1,1′′-[9,10-anthracenediylbis(methylene)]bis[9-hydroxy-6′-methoxy-cinchonanium chloride, Quinidine DerivativeMichael, Michael Addition, Vinylogous Michael Addition Michael addition, 2,3-substituted 3-oxopropanoate, 1-substituted ethene, 2,2,3-tritrisubstituted-(S)-3-oxopropanoate, 1,1′′-[9,10-anthracenediylbis(methylene)]bis[9-hydroxy-6′-methoxy-cinchonanium chloride, Quinine DerivativeMichael, Michael Addition, Vinylogous Michael Addition Michael Addition, substituted 2-oxocyclopentane-1-carboxylate, 4-substituted (E)-4-(2-nitrovinyl)benzene, 4-substituted (S)-1-((R)-1-(phenyl)-2-nitroethyl)-2-oxocyclopentane-1-carboxylate, Poly[sulfonyl-1,3-phenylenesulfonylamino[(8α,9S,10E)-cinchonan-9,11-diyl]-1,4-phenylene[(8α,9S,10E)-cinchonan-11,9-diyl]imino], Cinchonidin DerivativeMichael, Michael Addition Diels Alder reaction, 4,5-substitutded-3-hydroxy-2H-pyran-2-one, 2-substituted-cyclopent-4-ene-1,3-dione, 2,5,6-substituted (4R,7R,7aR)-7-hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-(epoxymethano)indene-1,3,8(2H)-trione, N-(8α,9S)-cinchonan-9-yl-N′-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-thiourea, Cinchonidine DerivativeCycloaddition, Diels-Alder reaction Spirocyclization, (E)-7-chloro-3-ethylidene-1-methylindolin-2-one, diethyl 2-((2,2,2-trifluoroethyl)imino)malonate, diethyl (2’R,3R,4’S)-7-chloro-1,4′-dimethyl-2-oxo-2′-(trifluoromethyl)spiro[indoline-3,3′-pyrrolidine]-5′,5′-dicarboxylate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [(8α,9S)-cinchonan-9-ylamino]- 3-Cyclobutene-1,2-dione, Cinchonidine Derivative[3+2]-Cycloaddition, Cycloaddition, Spirocyclization Aldol reaction, 3-(4-fluorophenyl)-3-oxopropanoic acid, tert-butyl 2,3-dioxoindoline-1-carboxylate, tert-butyl (R)-3-(2-(4-fluorophenyl)-2-oxoethyl)-3-hydroxy-2-oxoindoline-1-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeAldol, Aldol Decarboxylative aldol reaction, 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-oxo-3-phenoxypropanoic acid, 3-nitrobenzaldehyde, phenyl (2R,3R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxy-3-(3-nitrophenyl)propanoate, N-(9R)-cinchonan-9-yl-2,3,4-trimethoxy-benzenesulfonamide, Cinchonidine DerivativeAldol, Aldol Decarboxylative aldol reaction, 2-fluoro-3-((4-methoxyphenyl)thio)-3-oxopropanoic acid, 4,7-dichloro-1-methylindoline-2,3-dione, S-(4-methoxyphenyl) (R)-2-((R)-4,7-dichloro-3-hydroxy-1-methyl-2-oxoindolin-3-yl)-2-fluoroethanethioate, N-(8α,9S)-cinchonan-9-yl-3,5-bis(trifluoromethyl)-benzenesulfonamide, Cinchonidine DerivativeAldol, Aldol Cyanation of acylsilanes, 1-(tert-butyldimethylsilyl)-4-phenylbutan-1-one, trimethylsilanecarbonitrile, (S)-2-(tert-butyldimethylsilyl)-2-hydroxy-5-phenylpentanenitrile, 1,4-bis[[(8α,9R)-10,11-dihydro-6′-methoxy- cinchonan-9-yl]oxy]-9,10-Anthracenedione, Dihydroquinine DerivativeCyanation« Older EntriesNext Entries »
Cyanation of unsaturated ketones, tert-butyl (E)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-2-methylbenzoate, 2-hydroxy-2-methylpropanenitrile, cyanopotassium, tert-butyl (R)-4-(3-cyano-3-(3,5-dichlorophenyl)-4,4,4-trifluorobutanoyl)-2-methylbenzoate, 9-hydroxy-6′-methoxy-1-[(2,3,4,5,6-pentafluorophenyl)methyl]-cinchonanium bromide, Quinine DerivativeCyanation
Michael addition, 2,3-substituted 3-oxopropanoate, 1-substituted ethene, 2,2,3-tritrisubstituted-(R)-3-oxopropanoate, 1,1′′-[9,10-anthracenediylbis(methylene)]bis[9-hydroxy-6′-methoxy-cinchonanium chloride, Quinidine DerivativeMichael, Michael Addition, Vinylogous Michael Addition
Michael addition, 2,3-substituted 3-oxopropanoate, 1-substituted ethene, 2,2,3-tritrisubstituted-(S)-3-oxopropanoate, 1,1′′-[9,10-anthracenediylbis(methylene)]bis[9-hydroxy-6′-methoxy-cinchonanium chloride, Quinine DerivativeMichael, Michael Addition, Vinylogous Michael Addition
Michael Addition, substituted 2-oxocyclopentane-1-carboxylate, 4-substituted (E)-4-(2-nitrovinyl)benzene, 4-substituted (S)-1-((R)-1-(phenyl)-2-nitroethyl)-2-oxocyclopentane-1-carboxylate, Poly[sulfonyl-1,3-phenylenesulfonylamino[(8α,9S,10E)-cinchonan-9,11-diyl]-1,4-phenylene[(8α,9S,10E)-cinchonan-11,9-diyl]imino], Cinchonidin DerivativeMichael, Michael Addition
Diels Alder reaction, 4,5-substitutded-3-hydroxy-2H-pyran-2-one, 2-substituted-cyclopent-4-ene-1,3-dione, 2,5,6-substituted (4R,7R,7aR)-7-hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-(epoxymethano)indene-1,3,8(2H)-trione, N-(8α,9S)-cinchonan-9-yl-N′-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-thiourea, Cinchonidine DerivativeCycloaddition, Diels-Alder reaction
Spirocyclization, (E)-7-chloro-3-ethylidene-1-methylindolin-2-one, diethyl 2-((2,2,2-trifluoroethyl)imino)malonate, diethyl (2’R,3R,4’S)-7-chloro-1,4′-dimethyl-2-oxo-2′-(trifluoromethyl)spiro[indoline-3,3′-pyrrolidine]-5′,5′-dicarboxylate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [(8α,9S)-cinchonan-9-ylamino]- 3-Cyclobutene-1,2-dione, Cinchonidine Derivative[3+2]-Cycloaddition, Cycloaddition, Spirocyclization
Aldol reaction, 3-(4-fluorophenyl)-3-oxopropanoic acid, tert-butyl 2,3-dioxoindoline-1-carboxylate, tert-butyl (R)-3-(2-(4-fluorophenyl)-2-oxoethyl)-3-hydroxy-2-oxoindoline-1-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeAldol, Aldol
Decarboxylative aldol reaction, 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-oxo-3-phenoxypropanoic acid, 3-nitrobenzaldehyde, phenyl (2R,3R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxy-3-(3-nitrophenyl)propanoate, N-(9R)-cinchonan-9-yl-2,3,4-trimethoxy-benzenesulfonamide, Cinchonidine DerivativeAldol, Aldol
Decarboxylative aldol reaction, 2-fluoro-3-((4-methoxyphenyl)thio)-3-oxopropanoic acid, 4,7-dichloro-1-methylindoline-2,3-dione, S-(4-methoxyphenyl) (R)-2-((R)-4,7-dichloro-3-hydroxy-1-methyl-2-oxoindolin-3-yl)-2-fluoroethanethioate, N-(8α,9S)-cinchonan-9-yl-3,5-bis(trifluoromethyl)-benzenesulfonamide, Cinchonidine DerivativeAldol, Aldol
Cyanation of acylsilanes, 1-(tert-butyldimethylsilyl)-4-phenylbutan-1-one, trimethylsilanecarbonitrile, (S)-2-(tert-butyldimethylsilyl)-2-hydroxy-5-phenylpentanenitrile, 1,4-bis[[(8α,9R)-10,11-dihydro-6′-methoxy- cinchonan-9-yl]oxy]-9,10-Anthracenedione, Dihydroquinine DerivativeCyanation