Michael Addition, α,β‐unsaturated acyl pyrazoles, benzyl 2-nitroacetate, hydrogen, (S)-4-nitro-3-phenyl-1-(1H-pyrazol-1-yl)butan-1-one, palladium, 3,4-Bis[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition Oxa-Michael, substituted 5-methylenethiazol-4-one, substituted 3-(propan-2-ylidene)indolin-2-one, thiazolopyran derivatives, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [(8α,9S)-cinchonan-9-ylamino]- 3-Cyclobutene-1,2-dione, Cinchonidine DerivativeMichael Addition, Oxa-Michael Addition, Vinylogous Michael Addition Cyclization, 2,3-dioxopyrrolidines, allyl aryl ketones, substituted (S)-2-(6-benzyl-7-oxo-2,3,4,5,6,7-hexahydropyrano[2,3-c]pyrrol-2-yl)acetaldehyde, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCyclization, Cycloaddition Alkynylation, substituted methyl 2,2,5-trimethylhexanoate, primary alkynes, substituted 4,7,7-trimethyloct-2-yne, copper(I)-catalyst, 2-[Bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]benzamide, Quinine DerivativeAlkynylation Aza-Friedel-Crafts reaction, 3-aminobenzofurans, isatin-derived ketimines, substituted tert-butyl (R)-(3-(3-aminobenzofuran-2-yl)-2-oxoindolin-3-yl)carbamate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Friedel-Crafts, Friedel-Crafts Mannich reaction, 5-chlorobenzo[d]oxazol-2-amine, aldehydes, malonates, β-amino ester derivatives, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMannich, Mannich Hydrogenation of Imines, methyl (E)-3-(4-bromophenyl)-3-((4-methoxyphenyl)imino)propanoate, trichlorosilane, methyl (S)-3-(4-bromophenyl)-3-((4-methoxyphenyl)amino)propanoate, 2-[[(8α,9S)-cinchonan-9-ylamino]carbonyl]-1-methyl-Pyridinium tetrafluoroborate, Cinchonidine DerivativeFurther reactions, Hydrogenation, Hydrogenation of imines, Hydrosilylation Oxa-Michael, 3-(pyrrolidin-1-yl)phenol, 2,6-dichlorophenyl (E)-2-diazo-4-phenylbut-3-enoate, 2,3-disubstituted dihydrobenzofurans, rhodium catalyst, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Oxa-Michael Addition Alkylation, aliphatic amines, 2-chloro-N,2-diphenylacetamide, (S)-2-morpholino-N,2-diphenylacetamide, copper(I) iodide, N-[(S)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](6-methoxy-4-quinolinyl)methyl]-8-quinolinesulfonamide, Quinine DerivativeAlkylation, Alkylation [2+2] cycloaddition, ketenes, imines, azetidin-2-ones, Benzoylquinine, Quinine Derivative[2+2]-Cycloaddition, Cycloaddition« Older EntriesNext Entries »
Michael Addition, α,β‐unsaturated acyl pyrazoles, benzyl 2-nitroacetate, hydrogen, (S)-4-nitro-3-phenyl-1-(1H-pyrazol-1-yl)butan-1-one, palladium, 3,4-Bis[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeMichael, Michael Addition
Oxa-Michael, substituted 5-methylenethiazol-4-one, substituted 3-(propan-2-ylidene)indolin-2-one, thiazolopyran derivatives, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [(8α,9S)-cinchonan-9-ylamino]- 3-Cyclobutene-1,2-dione, Cinchonidine DerivativeMichael Addition, Oxa-Michael Addition, Vinylogous Michael Addition
Cyclization, 2,3-dioxopyrrolidines, allyl aryl ketones, substituted (S)-2-(6-benzyl-7-oxo-2,3,4,5,6,7-hexahydropyrano[2,3-c]pyrrol-2-yl)acetaldehyde, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCyclization, Cycloaddition
Alkynylation, substituted methyl 2,2,5-trimethylhexanoate, primary alkynes, substituted 4,7,7-trimethyloct-2-yne, copper(I)-catalyst, 2-[Bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]benzamide, Quinine DerivativeAlkynylation
Aza-Friedel-Crafts reaction, 3-aminobenzofurans, isatin-derived ketimines, substituted tert-butyl (R)-(3-(3-aminobenzofuran-2-yl)-2-oxoindolin-3-yl)carbamate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Friedel-Crafts, Friedel-Crafts
Mannich reaction, 5-chlorobenzo[d]oxazol-2-amine, aldehydes, malonates, β-amino ester derivatives, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMannich, Mannich
Hydrogenation of Imines, methyl (E)-3-(4-bromophenyl)-3-((4-methoxyphenyl)imino)propanoate, trichlorosilane, methyl (S)-3-(4-bromophenyl)-3-((4-methoxyphenyl)amino)propanoate, 2-[[(8α,9S)-cinchonan-9-ylamino]carbonyl]-1-methyl-Pyridinium tetrafluoroborate, Cinchonidine DerivativeFurther reactions, Hydrogenation, Hydrogenation of imines, Hydrosilylation
Oxa-Michael, 3-(pyrrolidin-1-yl)phenol, 2,6-dichlorophenyl (E)-2-diazo-4-phenylbut-3-enoate, 2,3-disubstituted dihydrobenzofurans, rhodium catalyst, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Oxa-Michael Addition
Alkylation, aliphatic amines, 2-chloro-N,2-diphenylacetamide, (S)-2-morpholino-N,2-diphenylacetamide, copper(I) iodide, N-[(S)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](6-methoxy-4-quinolinyl)methyl]-8-quinolinesulfonamide, Quinine DerivativeAlkylation, Alkylation
[2+2] cycloaddition, ketenes, imines, azetidin-2-ones, Benzoylquinine, Quinine Derivative[2+2]-Cycloaddition, Cycloaddition