Spirocyclization, oxindoles, (E)-4-mercaptobut-2-enoates, spirocyclic oxindoles, (1S,2R,4S,5R)-2-((S)-hydroxy(6-methoxyquinolin-4-yl)methyl)-1-((10-phenylanthracen-9-yl)methyl)-5-vinylquinuclidin-1-ium chloride, Quinidine DerivativeMichael Addition, Spirocyclization, Sulfa-Michael, Sulfa-Michael Addition Amination, tertiary amides, heptafluorobutyl sulfamate, heptafluorobutyl (R)-(1-(2-fluorophenyl)-4-(methyl(phenyl)amino)-4-oxobutyl)sulfamate, rhodium complexes, (9S)-11,12-dihydro-9-hydroxy-6′-methoxy-1-([1,1′:3′,1′′-terphenyl]-5′-ylmethyl)-cinchonanium, Dihydroquinidine DerivativeAmination, gamma-Amination Atropisomer Synthesis, 2-Arylindoles, arylmethylbromides, atropisomeric indoles, (9S)-1-[(2-methylphenyl)methyl]-9-(phenylmethoxy)-cinchonanium bromide, Cinchonine DerivativeAtropisomer synthesis, Dynamic Kinetic Resolution, Resolution Desymmetrization, keto sulfonium salts, (R,E)-5-(methylthio)-1,5-diphenylpent-1-en-3-one, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonine DerivativeDesymmetrization Trifluoromethylation, alkynyl ketones, trimethylsilyl trifluoromethane, trifluoromethylated alkynyl alcohols, (9S)-(9′′S)-1,1′′-[1,3-phenylenebis(methylene)]bis[9-hydroxy-cinchonanium bromide (1:2), Cinchonine DerivativeFluorination, Fluoromethylation, Trifluoromethylation Aldol reaction, substituted 3-(2-aminoethyl)indolin-2-one, formaldehyde, substituted (S)-3-(2-aminoethyl)-3-(hydroxymethyl)indolin-2-one, N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-thiourea, Cinchonine DerivativeAldol, Aldol Addition, isatins, α‐amido malonic acid half oxyesters, substituted (S)-2-amino-2-((S)-3-hydroxy-2-oxoindolin-3-yl)acetate, N-(9R)-cinchonan-9-yl-N′-methyl-thiourea, Cinchonine DerivativeAddition Michael Addition, hydantoins, tert-butyl acrylate, chiral hydantoins, (8α,9R)-1-([1,1′-biphenyl]-3-ylmethyl)-9-hydroxy-cinchonanium bromide, Cinchonine DerivativeMichael, Michael Addition Michael Addition, nitroalkenes, α-lithiated phosphonates, 1,2-disubstituted diethyl 3-nitropropylphosphonate, Cinchonine BaseMichael, Michael Addition Mannich reaction, 4-benzyl-2-phenyloxazol-5(4H)-one, ethyl 2-((4-methylphenyl)sulfonamido)acrylate, α,β-diamino diacid derivatives, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeMannich, Mannich« Older Entries
Spirocyclization, oxindoles, (E)-4-mercaptobut-2-enoates, spirocyclic oxindoles, (1S,2R,4S,5R)-2-((S)-hydroxy(6-methoxyquinolin-4-yl)methyl)-1-((10-phenylanthracen-9-yl)methyl)-5-vinylquinuclidin-1-ium chloride, Quinidine DerivativeMichael Addition, Spirocyclization, Sulfa-Michael, Sulfa-Michael Addition
Amination, tertiary amides, heptafluorobutyl sulfamate, heptafluorobutyl (R)-(1-(2-fluorophenyl)-4-(methyl(phenyl)amino)-4-oxobutyl)sulfamate, rhodium complexes, (9S)-11,12-dihydro-9-hydroxy-6′-methoxy-1-([1,1′:3′,1′′-terphenyl]-5′-ylmethyl)-cinchonanium, Dihydroquinidine DerivativeAmination, gamma-Amination
Atropisomer Synthesis, 2-Arylindoles, arylmethylbromides, atropisomeric indoles, (9S)-1-[(2-methylphenyl)methyl]-9-(phenylmethoxy)-cinchonanium bromide, Cinchonine DerivativeAtropisomer synthesis, Dynamic Kinetic Resolution, Resolution
Desymmetrization, keto sulfonium salts, (R,E)-5-(methylthio)-1,5-diphenylpent-1-en-3-one, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonine DerivativeDesymmetrization
Trifluoromethylation, alkynyl ketones, trimethylsilyl trifluoromethane, trifluoromethylated alkynyl alcohols, (9S)-(9′′S)-1,1′′-[1,3-phenylenebis(methylene)]bis[9-hydroxy-cinchonanium bromide (1:2), Cinchonine DerivativeFluorination, Fluoromethylation, Trifluoromethylation
Aldol reaction, substituted 3-(2-aminoethyl)indolin-2-one, formaldehyde, substituted (S)-3-(2-aminoethyl)-3-(hydroxymethyl)indolin-2-one, N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-thiourea, Cinchonine DerivativeAldol, Aldol
Addition, isatins, α‐amido malonic acid half oxyesters, substituted (S)-2-amino-2-((S)-3-hydroxy-2-oxoindolin-3-yl)acetate, N-(9R)-cinchonan-9-yl-N′-methyl-thiourea, Cinchonine DerivativeAddition
Michael Addition, hydantoins, tert-butyl acrylate, chiral hydantoins, (8α,9R)-1-([1,1′-biphenyl]-3-ylmethyl)-9-hydroxy-cinchonanium bromide, Cinchonine DerivativeMichael, Michael Addition
Michael Addition, nitroalkenes, α-lithiated phosphonates, 1,2-disubstituted diethyl 3-nitropropylphosphonate, Cinchonine BaseMichael, Michael Addition
Mannich reaction, 4-benzyl-2-phenyloxazol-5(4H)-one, ethyl 2-((4-methylphenyl)sulfonamido)acrylate, α,β-diamino diacid derivatives, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeMannich, Mannich