Highly Asymmetric Michael Addition to a,b-Unsaturated Ketones Catalyzed by 9-Amino-9-deoxyepiquinine.

DOI Number:

10.1002/anie.200603612

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

2-(thiochroman-4-ylidene)malononitrile, (E)-4-phenylbut-3-en-2-one

Product:

2-((S)-3-((R)-3-oxo-1-phenylbutyl)thiochroman-4-ylidene)malononitrile

Catalyst:

(8α,9S)-6′-Methoxycinchonan-9-amine

Cas No:

168960-95-0

Cas No:

130-95-0