Organocatalytic enantioselective direct vinylogous michael addition of α,β-unsaturated γ-butyrolactam to β-acyl acrylates and 1,2-diacylethylenes.
DOI Number:
10.1021/jo5027047
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
β-acyl acrylates, 1,2-diacylethylenes, α,β-unsaturated γ-butyrolactam
Product:
substituted (R)-2-((R)-5-oxo-2,5-dihydro-1H-pyrrol-2-yl)succinaldehyde
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-25-8
Associated Product from Buchler GmbH:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-25-8