Mechanism and origins of stereoinduction in natural cinchona alkaloid catalyzed asymmetric electrophilic trifluoromethylthiolation of β-keto esters with N-trifluoromethylthiophthalimide as electrophilic SCF3 source.
DOI Number:
10.1021/acscatal.7b03007
Reaction Category:
Educt:
beta-keto esters, N-trifluoromethylthiophthalimide
Product:
tert-butyl (S)-4-methyl-2-oxo-1-((trifluoromethyl)thio)cyclopent-3-ene-1-carboxylate
Catalyst:
Quinidine Base
Cas No:
56-54-2
Associated Product from Buchler GmbH:
Quinidine Base
Cas No:
56-54-2