Cinchona alkaloid-catalyzed asymmetric trifluoromethylation of alkynyl ketones with trimethylsilyl trifluoromethane.
DOI Number:
10.1021/ol102189c
Reaction Category:
MOP ID:
MOP_0000368
Educt:
alkynyl ketones, trimethylsilyl trifluoromethane
Product:
trifluoromethylated alkynyl alcohols
Catalyst:
(9S)-(9′′S)-1,1′′-[1,3-phenylenebis(methylene)]bis[9-hydroxy-cinchonanium bromide (1:2)
Cas No:
479070-35-4
Associated Product from Buchler GmbH:
Cinchonine Base
Cas No:
118-10-5