Catalytic asymmetric conjugate addition of simple alkyl thiols to α,β-unsaturated N-acylated oxazolidin-2-ones with bifunctional catalysts.

DOI Number:

10.1021/ja8085092
Link to literature

Reaction Category:

Michael Addition | Sulfa-Michael | Sulfa-Michael Addition

RXNO ID:

RXNO_0000009

Educt:

α,β-unsaturated N-acylated oxazolidin-2-ones, alkyl thiols

Product:

γ-thio ketones

Catalyst:

N-[(9S)-9-(9-anthracenylmethoxy)cinchonan-6′-yl]-N′-[3,5-bis(trifluoromethyl)phenyl]-thiourea

Cas No:

1101868-74-9

Associated Product from Buchler GmbH:

6´-Aminocinchonine Base

Cas No:

2143936-31-4