Enantioselective catalytic Strecker reaction on cyclic (Z)-aldimines in flow: reaction optimization and sustainability aspects.
DOI Number:
10.1007/s41981-023-00279-9
Reaction Category:
RXNO ID:
RXNO_0000207
Educt:
spiro[cyclohexane-1,3'-indole], ethyl carbonocyanidate
Product:
(S)-spiro[cyclohexane-1,3'-indoline]-2'-carbonitrile
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-25-8
Associated Product from Buchler GmbH:
Quinidine Base
Cas No:
56-54-2