Organocatalytic enantioselective Strecker reaction of cyclic trifluoromethyl-ketoimines.

DOI Number:

10.1016/j.tetlet.2012.12.119

Reaction Category:

RXNO ID:

RXNO_0000207

Educt:

cyclic trifluoromethyl-ketoimines, trimethylsilyl cyanide

Product:

substituted 1-(4-methoxybenzyl)-2-oxo-1,2,3,4-tetrahydroquinazoline-4-carbonitrile

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7