Catalytic enantioselective Strecker reaction of isatin-derived N-unsubstituted ketimines.

DOI Number:

10.1021/acs.orglett.1c01194
Link to literature

Reaction Category:

Strecker

RXNO ID:

RXNO_0000207

Educt:

1-benzyl-7-fluoro-3-iminoindolin-2-one, trimethylsilanecarbonitrile

Product:

(S)-3-amino-1-benzyl-7-fluoro-2-oxoindoline-3-carbonitrile

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0