Highly Diastereo-and Enantioselective Synthesis of Spiro-tetrahydrofuran-pyrazolones via Organocatalytic Cascade Reaction between γ-Hydroxyenones and Unsaturated Pyrazolones.

DOI Number:

10.1021/acs.joc.8b00781

Reaction Category:

Educt:

unsaturated pyrazolones, γ-hydroxyenones

Product:

spiro-tetrahydrofuran-pyrazolones

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Cas No:

130-95-0