Asymmetric construction of spiro[thiopyranoindole-benzoisothiazole]scaffold via a formal [3+3] spiroannulation.

DOI Number:

10.1021/acs.orglett.5b01951
Link to literature

Reaction Category:

Spirocyclization

Educt:

substituted indoline-2-thione, E-substituted 3-vinylbenzo[d]isothiazole 1,1-dioxide

Product:

spiro[thiopyranoindole-benzoisothiazole]scaffold

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0