The Squaramide‐Catalyzed 1,3‐Dipolar Cycloaddition of Nitroalkenes with N‐2,2,2‐Trifluoroethylisatin Ketimines: An Approach for the Synthesis of 5′‐Trifluoromethyl‐spiro [pyrrolidin‐3,2′‐oxindoles].
DOI Number:
10.1002/adsc.201500416
Reaction Category:
Educt:
substituted (E)-3-((2,2,2-trifluoroethyl)imino)indolin-2-one, substituted (E)-nitroethene
Product:
substituted (3R,3'R,5'R)-3'-nitro-5'-(trifluoromethyl)spiro[indoline-3,2'-pyrrolidin]-2-one
Catalyst:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione
Cas No:
1256245-86-9
Associated Product from Buchler GmbH:
Cinchonidine Base
Cas No:
485-71-2