Expanding the Scope of Primary Amine Catalysis: Stereoselective Synthesis of Indanedione-Fused 2,6-Disubstituted trans-Spirocyclohexanones.

DOI Number:

10.1021/acs.joc.5b02921
Link to literature

Reaction Category:

Cycloaddition | Diels-Alder reaction | Michael | Michael Addition | Spirocyclization

RXNO ID:

RXNO_0000006

Educt:

substituted 2-methylene-1,3-Indandione, alpha,beta-unsaturated ketones

Product:

indanedione-fused 2,6-disubstituted trans-spirocyclohexanones

Catalyst:

(9R)-Cinchonan-9-amine

Cas No:

168960-96-1

Associated Product from Buchler GmbH:

Cinchonine Base

Cas No:

118-10-5