Contemporary asymmetric phase transfer catalysis: large-scale industrial applications.

DOI Number:

10.1021/acs.oprd.5b00304

Reaction Category:

Educt:

N,N-dibenzyl-3-(chloromethyl)-4-(hydroxymethyl)benzenaminium chloride, methyl 1-(tert-butyl)-2-hydroxy-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate

Product:

(R)-1'-(tert-butyl)-5-(dibenzylamino)-1,3-dihydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one

Catalyst:

1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-(9R)-cinchonanium bromide

Cas No:

947508-16-9

Associated Product from Buchler GmbH:

N-3,5-bis(trifluoromethyl)benzyl-cinchonidinium Bromide

Cas No:

947508-16-9