Quinine-catalyzed asymmetric domino Michael-cyclization reaction for the synthesis of spirocyclic oxindoles bearing two spiro quaternary centers and three consecutive stereocenters.

DOI Number:

10.1016/j.tet.2014.01.036

Reaction Category:

Educt:

3-isothiocyanato oxindoles, unsaturated pyrazolones

Product:

spirocyclic oxindoles

Catalyst:

Quinine Base

Cas No:

130-95-0

Cas No:

130-95-0