Asymmetric synthesis of spiro-3,4-dihydropyrans via a domino organocatalytic sequence.

DOI Number:

10.1021/ol1007873
Link to literature

Reaction Category:

Spirocyclization

Educt:

2-oxocyclyclic-carbaldehydes, (E)-substituted 2-oxobut-3-enoates

Product:

spiro-3,4-dihydropyrans

Catalyst:

(9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)] bis[10,11-dihydro-6′-methoxy-cinchonan]

Cas No:

149725-81-5

Associated Product from Buchler GmbH:

Dihydroquinidine Base

Cas No:

1435-55-8