Bifuctional amino-squaramides catalyzed asymmetric spiroannulation cascades with aliphatic β, γ-unsaturated α-keto esters: controlling an aldehyde enolate.
DOI Number:
10.1021/jo202633c
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
2-oxocyclohexane-1-carbaldehyde, aliphatic beta,gamma-unsaturated α-keto esters
Product:
substituted (6R)-1,7-dioxo-2-oxaspiro[5.5]undecane-3-carboxylate
Catalyst:
3-((3,5-bis(trifluoromethyl)benzyl)amino)-4-(((R)-(6-methoxyquinolin-4-yl) ((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione
Cas No:
1073917-09-5
Associated Product from Buchler GmbH:
Quinidine Base
Cas No:
56-54-2