Catalytic Asymmetric Mannich/Cyclization of 2-Isothiocyanato-1-indanones: An Approach to the Synthesis of Bispirocyclic Indanone–Thioimidazolidine–Oxindoles.
DOI Number:
10.1021/acs.orglett.8b01389
Reaction Category:
Educt:
2-Isothiocyanato-1-indanones, substituted 3-iminoindolin-2-one
Product:
substituted (2S,5'R)-2'-thioxodispiro[indene-2,4'-imidazolidine-5',3''-indoline]-1,2''(3H)-dione
Catalyst:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1256245-84-7
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0