Bifunctional squaramide-catalyzed asymmetric [3+2] cyclization of 2-(1-methyl-2-oxoindolin-3-yl) malononitriles with unsaturated pyrazolones to construct spirooxindole-fused spiropyrazolones.
DOI Number:
10.1021/acs.joc.9b01268
Reaction Category:
Educt:
2-(1-methyl-2-oxoindolin-3-yl) malononitriles, unsaturated pyrazolones
Product:
spirooxindole-fused spiropyrazolones
Catalyst:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1256245-84-7
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0