Organocatalytic asymmetric halogenation/semipinacol rearrangement: highly efficient synthesis of chiral α-oxa-quaternary β-haloketones.
DOI Number:
10.1021/ja201794v
Reaction Category:
MOP ID:
MOP_0000551
Educt:
disubstituted (3,4-dihydro-2H-pyran-6-yl)methanol, N-Bromoacetamide, 1,3-Dichloro-5,5-diphenyl-2,4-imidazolidinedione
Product:
chiral α-oxa-quaternary β-haloketones
Catalyst:
(9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxy-cinchonan]
Cas No:
149725-81-5
Associated Product from Buchler GmbH:
Dihydroquinidine Base
Cas No:
1435-55-8