Synthesis of Novel Pseudo-Enantiomeric Phase-Transfer Catalysts from Cinchona Alkaloids and Application to the Hydrolytic Dynamic Kinetic Resolution of Racemic 3-Phenyl-2-oxetanone.

DOI Number:

10.1248/cpb.c24-00406

Reaction Category:

Educt:

3-phenyloxetan-2-one, OH-donors

Product:

(S)-3-hydroxy-2-phenylpropanoic acid

Catalyst:

9-hydroxy-6′-methoxy-1-(phenylmethyl)-(9S)-cinchonanium chloride

Cas No:

77481-82-4

Associated Product from Buchler GmbH:

N-Benzylquinidinium Chloride

Cas No:

77481-82-4